Is the shielding effect of cholecalciferol in SARS CoV-2 infection dependable? An evidence based unraveling

Despite being announced as a global health concern and emergency in January by WHO, designing specific treatment for SARS-CoV-2 is still a summit yet to be conquered. Currently, many drugs are being tested in the clinical scenario and vitamins play a significant role in therapeutic management. Based...

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Detalles Bibliográficos
Autores principales: Lahoor Basha, Shaik, Suresh, Sake, Ashok Reddy, V.V., Surya Teja, S P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier, a division of RELX India, Pvt. Ltd on behalf of INDIACLEN. 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576325/
https://www.ncbi.nlm.nih.gov/pubmed/33102933
http://dx.doi.org/10.1016/j.cegh.2020.10.005
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author Lahoor Basha, Shaik
Suresh, Sake
Ashok Reddy, V.V.
Surya Teja, S P
author_facet Lahoor Basha, Shaik
Suresh, Sake
Ashok Reddy, V.V.
Surya Teja, S P
author_sort Lahoor Basha, Shaik
collection PubMed
description Despite being announced as a global health concern and emergency in January by WHO, designing specific treatment for SARS-CoV-2 is still a summit yet to be conquered. Currently, many drugs are being tested in the clinical scenario and vitamins play a significant role in therapeutic management. Based on the available evidence, we postulate that maintaining normal vitamin D(3) levels may reduce severity, mortality risk of COVID-19. This review elucidates the alarming need for randomized clinical trials to determine the role of vitamin D in patient prognosis in COVID-19 infection and on latitude bases epidemiological outcome.
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spelling pubmed-75763252020-10-21 Is the shielding effect of cholecalciferol in SARS CoV-2 infection dependable? An evidence based unraveling Lahoor Basha, Shaik Suresh, Sake Ashok Reddy, V.V. Surya Teja, S P Clin Epidemiol Glob Health Review Article Despite being announced as a global health concern and emergency in January by WHO, designing specific treatment for SARS-CoV-2 is still a summit yet to be conquered. Currently, many drugs are being tested in the clinical scenario and vitamins play a significant role in therapeutic management. Based on the available evidence, we postulate that maintaining normal vitamin D(3) levels may reduce severity, mortality risk of COVID-19. This review elucidates the alarming need for randomized clinical trials to determine the role of vitamin D in patient prognosis in COVID-19 infection and on latitude bases epidemiological outcome. The Authors. Published by Elsevier, a division of RELX India, Pvt. Ltd on behalf of INDIACLEN. 2021 2020-10-21 /pmc/articles/PMC7576325/ /pubmed/33102933 http://dx.doi.org/10.1016/j.cegh.2020.10.005 Text en © 2020 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review Article
Lahoor Basha, Shaik
Suresh, Sake
Ashok Reddy, V.V.
Surya Teja, S P
Is the shielding effect of cholecalciferol in SARS CoV-2 infection dependable? An evidence based unraveling
title Is the shielding effect of cholecalciferol in SARS CoV-2 infection dependable? An evidence based unraveling
title_full Is the shielding effect of cholecalciferol in SARS CoV-2 infection dependable? An evidence based unraveling
title_fullStr Is the shielding effect of cholecalciferol in SARS CoV-2 infection dependable? An evidence based unraveling
title_full_unstemmed Is the shielding effect of cholecalciferol in SARS CoV-2 infection dependable? An evidence based unraveling
title_short Is the shielding effect of cholecalciferol in SARS CoV-2 infection dependable? An evidence based unraveling
title_sort is the shielding effect of cholecalciferol in sars cov-2 infection dependable? an evidence based unraveling
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576325/
https://www.ncbi.nlm.nih.gov/pubmed/33102933
http://dx.doi.org/10.1016/j.cegh.2020.10.005
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