Novel ANO1 Inhibitor from Mallotus apelta Extract Exerts Anticancer Activity through Downregulation of ANO1

Anoctamin1 (ANO1), a calcium-activated chloride channel, is frequently overexpressed in several cancers, including human prostate cancer and oral squamous cell carcinomas. ANO1 plays a critical role in tumor growth and maintenance of these cancers. In this study, we have isolated two new compounds (...

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Detalles Bibliográficos
Autores principales: Seo, Yohan, Anh, Nguyen Hoang, Heo, Yunkyung, Park, So-Hyeon, Kiem, Phan Van, Lee, Yechan, Yen, Duong Thi Hai, Jo, Sungwoo, Jeon, Dongkyu, Tai, Bui Huu, Nam, Nguyen Hoai, Minh, Chau Van, Kim, Seung Hyun, Nhiem, Nguyen Xuan, Namkung, Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576493/
https://www.ncbi.nlm.nih.gov/pubmed/32899792
http://dx.doi.org/10.3390/ijms21186470

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