Dynamic differences between DNA damage repair responses in primary tumors and cell lines

The study of DNA damage repair response (DDR) in prostate cancer is restricted by the limited number of prostate cancer cell lines and lack of surrogates for heterogeneity in clinical samples. Here, we sought to leverage our experience with patient derived explants (PDEs) cultured ex vivo to study d...

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Detalles Bibliográficos
Autores principales: Gilbreath, Collin, Ma, Shihong, Yu, Lan, Sonavane, Rajni, Roggero, Carlos M., Devineni, Anvita, Mauck, Ryan, Desai, Neil B., Bagrodia, Aditya, Kittler, Ralf, Raj, Ganesh V., Yin, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576517/
https://www.ncbi.nlm.nih.gov/pubmed/33096336
http://dx.doi.org/10.1016/j.tranon.2020.100898

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