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High strength and low swelling composite hydrogels from gelatin and delignified wood

A delignified wood template with hydrophilic characteristics and high porosity was obtained by removal of lignin. Gelatin was infiltrated into the delignified wood and further crosslinked with a natural crosslinker genipin to form hydrogels. The composite hydrogels showed high mechanical strength un...

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Autores principales: Wang, Shennan, Li, Kai, Zhou, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576601/
https://www.ncbi.nlm.nih.gov/pubmed/33082476
http://dx.doi.org/10.1038/s41598-020-74860-w
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author Wang, Shennan
Li, Kai
Zhou, Qi
author_facet Wang, Shennan
Li, Kai
Zhou, Qi
author_sort Wang, Shennan
collection PubMed
description A delignified wood template with hydrophilic characteristics and high porosity was obtained by removal of lignin. Gelatin was infiltrated into the delignified wood and further crosslinked with a natural crosslinker genipin to form hydrogels. The composite hydrogels showed high mechanical strength under compression and low swelling in physiological condition. The effect of genipin concentrations (1, 50 and 100 mM) on structure and properties of the composite hydrogels were studied. A porous honeycomb structure with tunable pore size and porosity was observed in the freeze-dried composite hydrogels. High elastic modulus of 11.82 ± 1.51 MPa and high compressive yield stress of 689.3 ± 34.9 kPa were achieved for the composite hydrogel with a water content as high as 81%. The equilibrium water uptake of the freeze-dried hydrogel in phosphate buffered saline at 37 °C was as low as 407.5%. These enables the delignified wood structure an excellent template in composite hydrogel preparation by using infiltration and in-situ synthesis, particularly when high mechanical strength and stiffness are desired.
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spelling pubmed-75766012020-10-21 High strength and low swelling composite hydrogels from gelatin and delignified wood Wang, Shennan Li, Kai Zhou, Qi Sci Rep Article A delignified wood template with hydrophilic characteristics and high porosity was obtained by removal of lignin. Gelatin was infiltrated into the delignified wood and further crosslinked with a natural crosslinker genipin to form hydrogels. The composite hydrogels showed high mechanical strength under compression and low swelling in physiological condition. The effect of genipin concentrations (1, 50 and 100 mM) on structure and properties of the composite hydrogels were studied. A porous honeycomb structure with tunable pore size and porosity was observed in the freeze-dried composite hydrogels. High elastic modulus of 11.82 ± 1.51 MPa and high compressive yield stress of 689.3 ± 34.9 kPa were achieved for the composite hydrogel with a water content as high as 81%. The equilibrium water uptake of the freeze-dried hydrogel in phosphate buffered saline at 37 °C was as low as 407.5%. These enables the delignified wood structure an excellent template in composite hydrogel preparation by using infiltration and in-situ synthesis, particularly when high mechanical strength and stiffness are desired. Nature Publishing Group UK 2020-10-20 /pmc/articles/PMC7576601/ /pubmed/33082476 http://dx.doi.org/10.1038/s41598-020-74860-w Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Wang, Shennan
Li, Kai
Zhou, Qi
High strength and low swelling composite hydrogels from gelatin and delignified wood
title High strength and low swelling composite hydrogels from gelatin and delignified wood
title_full High strength and low swelling composite hydrogels from gelatin and delignified wood
title_fullStr High strength and low swelling composite hydrogels from gelatin and delignified wood
title_full_unstemmed High strength and low swelling composite hydrogels from gelatin and delignified wood
title_short High strength and low swelling composite hydrogels from gelatin and delignified wood
title_sort high strength and low swelling composite hydrogels from gelatin and delignified wood
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576601/
https://www.ncbi.nlm.nih.gov/pubmed/33082476
http://dx.doi.org/10.1038/s41598-020-74860-w
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