Systems biology analysis of the Clostridioides difficile core-genome contextualizes microenvironmental evolutionary pressures leading to genotypic and phenotypic divergence

Hospital acquired Clostridioides (Clostridium) difficile infection is exacerbated by the continued evolution of C. difficile strains, a phenomenon studied by multiple laboratories using stock cultures specific to each laboratory. Intralaboratory evolution of strains contributes to interlaboratory va...

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Detalles Bibliográficos
Autores principales: Norsigian, Charles J., Danhof, Heather A., Brand, Colleen K., Oezguen, Numan, Midani, Firas S., Palsson, Bernhard O., Savidge, Tor C., Britton, Robert A., Spinler, Jennifer K., Monk, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576604/
https://www.ncbi.nlm.nih.gov/pubmed/33082337
http://dx.doi.org/10.1038/s41540-020-00151-9

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