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Time course of altered DNA methylation evoked by critical illness and by early administration of parenteral nutrition in the paediatric ICU
BACKGROUND: A genome-wide study identified de novo DNA methylation alterations in leukocytes of children at paediatric intensive care unit (PICU) discharge, offering a biological basis for their impaired long-term development. Early parenteral nutrition (early-PN) in PICU, compared with omitting PN...
Autores principales: | Verlinden, Ines, Güiza, Fabian, Derese, Inge, Wouters, Pieter J., Joosten, Koen, Verbruggen, Sascha C., Van den Berghe, Greet, Vanhorebeek, Ilse |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576729/ https://www.ncbi.nlm.nih.gov/pubmed/33081814 http://dx.doi.org/10.1186/s13148-020-00947-w |
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