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Refining drug administration in a murine model of acute infection with Trypanosoma cruzi
BACKGROUND: In animal research, “refinement” refers to modifications of husbandry or experimental procedures to enhance animal well-being and minimize or eliminate pain and distress. Evaluation of drug efficacy in mice models, such as those used to study Trypanosoma cruzi infection, require prolonge...
Autores principales: | Gulin, Julián Ernesto Nicolás, Bisio, Margarita, García-Bournissen, Facundo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576763/ https://www.ncbi.nlm.nih.gov/pubmed/33094096 http://dx.doi.org/10.1186/s42826-020-00071-z |
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