Inhaled corticosteroids and the risk of type 2 diabetes among Swedish COPD patients

This study reports the association of ICS use and the risk of type 2 diabetes mellitus (T2DM) in Swedish patients with COPD using data from real-world, primary care settings. A total of 7078 patients with COPD were included in this analysis and the 5-year cumulative incidence rate per 100,000 person...

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Autores principales: Ställberg, Björn, Janson, Christer, Lisspers, Karin, Johansson, Gunnar, Gutzwiller, Florian S., Mezzi, Karen, Bjerregaard, Bine Kjoeller, Kejs, Anne Mette Tranberg, Jorgensen, Leif, Larsson, Kjell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576803/
https://www.ncbi.nlm.nih.gov/pubmed/33082331
http://dx.doi.org/10.1038/s41533-020-00207-7
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author Ställberg, Björn
Janson, Christer
Lisspers, Karin
Johansson, Gunnar
Gutzwiller, Florian S.
Mezzi, Karen
Bjerregaard, Bine Kjoeller
Kejs, Anne Mette Tranberg
Jorgensen, Leif
Larsson, Kjell
author_facet Ställberg, Björn
Janson, Christer
Lisspers, Karin
Johansson, Gunnar
Gutzwiller, Florian S.
Mezzi, Karen
Bjerregaard, Bine Kjoeller
Kejs, Anne Mette Tranberg
Jorgensen, Leif
Larsson, Kjell
author_sort Ställberg, Björn
collection PubMed
description This study reports the association of ICS use and the risk of type 2 diabetes mellitus (T2DM) in Swedish patients with COPD using data from real-world, primary care settings. A total of 7078 patients with COPD were included in this analysis and the 5-year cumulative incidence rate per 100,000 person years was 1506.9. The yearly incidence rate per 100,000 person years ranged from 850 to 1919. Use of ICS especially at a high dose in patients with COPD was related to an increased risk of T2DM.
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spelling pubmed-75768032020-10-23 Inhaled corticosteroids and the risk of type 2 diabetes among Swedish COPD patients Ställberg, Björn Janson, Christer Lisspers, Karin Johansson, Gunnar Gutzwiller, Florian S. Mezzi, Karen Bjerregaard, Bine Kjoeller Kejs, Anne Mette Tranberg Jorgensen, Leif Larsson, Kjell NPJ Prim Care Respir Med Brief Communication This study reports the association of ICS use and the risk of type 2 diabetes mellitus (T2DM) in Swedish patients with COPD using data from real-world, primary care settings. A total of 7078 patients with COPD were included in this analysis and the 5-year cumulative incidence rate per 100,000 person years was 1506.9. The yearly incidence rate per 100,000 person years ranged from 850 to 1919. Use of ICS especially at a high dose in patients with COPD was related to an increased risk of T2DM. Nature Publishing Group UK 2020-10-20 /pmc/articles/PMC7576803/ /pubmed/33082331 http://dx.doi.org/10.1038/s41533-020-00207-7 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Brief Communication
Ställberg, Björn
Janson, Christer
Lisspers, Karin
Johansson, Gunnar
Gutzwiller, Florian S.
Mezzi, Karen
Bjerregaard, Bine Kjoeller
Kejs, Anne Mette Tranberg
Jorgensen, Leif
Larsson, Kjell
Inhaled corticosteroids and the risk of type 2 diabetes among Swedish COPD patients
title Inhaled corticosteroids and the risk of type 2 diabetes among Swedish COPD patients
title_full Inhaled corticosteroids and the risk of type 2 diabetes among Swedish COPD patients
title_fullStr Inhaled corticosteroids and the risk of type 2 diabetes among Swedish COPD patients
title_full_unstemmed Inhaled corticosteroids and the risk of type 2 diabetes among Swedish COPD patients
title_short Inhaled corticosteroids and the risk of type 2 diabetes among Swedish COPD patients
title_sort inhaled corticosteroids and the risk of type 2 diabetes among swedish copd patients
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576803/
https://www.ncbi.nlm.nih.gov/pubmed/33082331
http://dx.doi.org/10.1038/s41533-020-00207-7
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