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Tracking personalized functional health in older adults using geriatric assessments

BACKGROUND: Higher levels of functional health in older adults leads to higher quality of life and improves the ability to age-in-place. Tracking functional health objectively could help clinicians to make decisions for interventions in case of health deterioration. Even though several geriatric ass...

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Autores principales: Mishra, Anup K., Skubic, Marjorie, Popescu, Mihail, Lane, Kari, Rantz, Marilyn, Despins, Laurel A., Abbott, Carmen, Keller, James, Robinson, Erin L., Miller, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576843/
https://www.ncbi.nlm.nih.gov/pubmed/33081769
http://dx.doi.org/10.1186/s12911-020-01283-y
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author Mishra, Anup K.
Skubic, Marjorie
Popescu, Mihail
Lane, Kari
Rantz, Marilyn
Despins, Laurel A.
Abbott, Carmen
Keller, James
Robinson, Erin L.
Miller, Steve
author_facet Mishra, Anup K.
Skubic, Marjorie
Popescu, Mihail
Lane, Kari
Rantz, Marilyn
Despins, Laurel A.
Abbott, Carmen
Keller, James
Robinson, Erin L.
Miller, Steve
author_sort Mishra, Anup K.
collection PubMed
description BACKGROUND: Higher levels of functional health in older adults leads to higher quality of life and improves the ability to age-in-place. Tracking functional health objectively could help clinicians to make decisions for interventions in case of health deterioration. Even though several geriatric assessments capture several aspects of functional health, there is limited research in longitudinally tracking personalized functional health of older adults using a combination of these assessments. METHODS: We used geriatric assessment data collected from 150 older adults to develop and validate a functional health prediction model based on risks associated with falls, hospitalizations, emergency visits, and death. We used mixed effects logistic regression to construct the model. The geriatric assessments included were Activities of Daily Living (ADL), Instrumental Activities of Daily Living (IADL), Mini-Mental State Examination (MMSE), Geriatric Depression Scale (GDS), and Short Form 12 (SF12). Construct validators such as fall risks associated with model predictions, and case studies with functional health trajectories were used to validate the model. RESULTS: The model is shown to separate samples with and without adverse health event outcomes with an area under the receiver operating characteristic curve (AUC) of > 0.85. The model could predict emergency visit or hospitalization with an AUC of 0.72 (95% CI 0.65–0.79), fall with an AUC of 0.86 (95% CI 0.83–0.89), fall with hospitalization with an AUC of 0.89 (95% CI 0.85–0.92), and mortality with an AUC of 0.93 (95% CI 0.88–0.97). Multiple comparisons of means using Turkey HSD test show that model prediction means for samples with no adverse health events versus samples with fall, hospitalization, and death were statistically significant (p < 0.001). Case studies for individual residents using predicted functional health trajectories show that changes in model predictions over time correspond to critical health changes in older adults. CONCLUSIONS: The personalized functional health tracking may provide clinicians with a longitudinal view of overall functional health in older adults to help address the early detection of deterioration trends and decide appropriate interventions. It can also help older adults and family members take proactive steps to improve functional health.
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spelling pubmed-75768432020-10-22 Tracking personalized functional health in older adults using geriatric assessments Mishra, Anup K. Skubic, Marjorie Popescu, Mihail Lane, Kari Rantz, Marilyn Despins, Laurel A. Abbott, Carmen Keller, James Robinson, Erin L. Miller, Steve BMC Med Inform Decis Mak Research Article BACKGROUND: Higher levels of functional health in older adults leads to higher quality of life and improves the ability to age-in-place. Tracking functional health objectively could help clinicians to make decisions for interventions in case of health deterioration. Even though several geriatric assessments capture several aspects of functional health, there is limited research in longitudinally tracking personalized functional health of older adults using a combination of these assessments. METHODS: We used geriatric assessment data collected from 150 older adults to develop and validate a functional health prediction model based on risks associated with falls, hospitalizations, emergency visits, and death. We used mixed effects logistic regression to construct the model. The geriatric assessments included were Activities of Daily Living (ADL), Instrumental Activities of Daily Living (IADL), Mini-Mental State Examination (MMSE), Geriatric Depression Scale (GDS), and Short Form 12 (SF12). Construct validators such as fall risks associated with model predictions, and case studies with functional health trajectories were used to validate the model. RESULTS: The model is shown to separate samples with and without adverse health event outcomes with an area under the receiver operating characteristic curve (AUC) of > 0.85. The model could predict emergency visit or hospitalization with an AUC of 0.72 (95% CI 0.65–0.79), fall with an AUC of 0.86 (95% CI 0.83–0.89), fall with hospitalization with an AUC of 0.89 (95% CI 0.85–0.92), and mortality with an AUC of 0.93 (95% CI 0.88–0.97). Multiple comparisons of means using Turkey HSD test show that model prediction means for samples with no adverse health events versus samples with fall, hospitalization, and death were statistically significant (p < 0.001). Case studies for individual residents using predicted functional health trajectories show that changes in model predictions over time correspond to critical health changes in older adults. CONCLUSIONS: The personalized functional health tracking may provide clinicians with a longitudinal view of overall functional health in older adults to help address the early detection of deterioration trends and decide appropriate interventions. It can also help older adults and family members take proactive steps to improve functional health. BioMed Central 2020-10-20 /pmc/articles/PMC7576843/ /pubmed/33081769 http://dx.doi.org/10.1186/s12911-020-01283-y Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Mishra, Anup K.
Skubic, Marjorie
Popescu, Mihail
Lane, Kari
Rantz, Marilyn
Despins, Laurel A.
Abbott, Carmen
Keller, James
Robinson, Erin L.
Miller, Steve
Tracking personalized functional health in older adults using geriatric assessments
title Tracking personalized functional health in older adults using geriatric assessments
title_full Tracking personalized functional health in older adults using geriatric assessments
title_fullStr Tracking personalized functional health in older adults using geriatric assessments
title_full_unstemmed Tracking personalized functional health in older adults using geriatric assessments
title_short Tracking personalized functional health in older adults using geriatric assessments
title_sort tracking personalized functional health in older adults using geriatric assessments
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576843/
https://www.ncbi.nlm.nih.gov/pubmed/33081769
http://dx.doi.org/10.1186/s12911-020-01283-y
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