Targeting the gut microbial metabolic pathway with small molecules decreases uremic toxin production

Uremic toxins are a class of toxins that accumulate in patients with chronic kidney disease (CKD). Indoxyl sulfate (IS), a typical uremic toxin, is not efficiently removed by hemodialysis. Modulation of IS production in the gut microbiota may be a promising strategy for decreasing IS concentration,...

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Detalles Bibliográficos
Autores principales: Wang, Yingyi, Li, Jianping, Chen, Chenkai, Lu, Jingbo, Yu, Jingao, Xu, Xuejun, Peng, Yin, Zhang, Sen, Jiang, Shu, Guo, Jianming, Duan, Jinao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577114/
https://www.ncbi.nlm.nih.gov/pubmed/33016221
http://dx.doi.org/10.1080/19490976.2020.1823800

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