Probing infectious disease by single-cell RNA sequencing: Progresses and perspectives

The increasing application of single-cell RNA sequencing (scRNA-seq) technology in life science and biomedical research has significantly increased our understanding of the cellular heterogeneities in immunology, oncology and developmental biology. This review will summarize the development of vario...

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Autores principales: Luo, Geyang, Gao, Qian, Zhang, Shuye, Yan, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577221/
https://www.ncbi.nlm.nih.gov/pubmed/33106757
http://dx.doi.org/10.1016/j.csbj.2020.10.016
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author Luo, Geyang
Gao, Qian
Zhang, Shuye
Yan, Bo
author_facet Luo, Geyang
Gao, Qian
Zhang, Shuye
Yan, Bo
author_sort Luo, Geyang
collection PubMed
description The increasing application of single-cell RNA sequencing (scRNA-seq) technology in life science and biomedical research has significantly increased our understanding of the cellular heterogeneities in immunology, oncology and developmental biology. This review will summarize the development of various scRNA-seq technologies; primarily discussing the application of scRNA-seq on infectious diseases, and exploring the current development, challenges, and potential applications of scRNA-seq technology in the future.
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spelling pubmed-75772212020-10-22 Probing infectious disease by single-cell RNA sequencing: Progresses and perspectives Luo, Geyang Gao, Qian Zhang, Shuye Yan, Bo Comput Struct Biotechnol J Review The increasing application of single-cell RNA sequencing (scRNA-seq) technology in life science and biomedical research has significantly increased our understanding of the cellular heterogeneities in immunology, oncology and developmental biology. This review will summarize the development of various scRNA-seq technologies; primarily discussing the application of scRNA-seq on infectious diseases, and exploring the current development, challenges, and potential applications of scRNA-seq technology in the future. Research Network of Computational and Structural Biotechnology 2020-10-21 /pmc/articles/PMC7577221/ /pubmed/33106757 http://dx.doi.org/10.1016/j.csbj.2020.10.016 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Luo, Geyang
Gao, Qian
Zhang, Shuye
Yan, Bo
Probing infectious disease by single-cell RNA sequencing: Progresses and perspectives
title Probing infectious disease by single-cell RNA sequencing: Progresses and perspectives
title_full Probing infectious disease by single-cell RNA sequencing: Progresses and perspectives
title_fullStr Probing infectious disease by single-cell RNA sequencing: Progresses and perspectives
title_full_unstemmed Probing infectious disease by single-cell RNA sequencing: Progresses and perspectives
title_short Probing infectious disease by single-cell RNA sequencing: Progresses and perspectives
title_sort probing infectious disease by single-cell rna sequencing: progresses and perspectives
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577221/
https://www.ncbi.nlm.nih.gov/pubmed/33106757
http://dx.doi.org/10.1016/j.csbj.2020.10.016
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