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Ex vivo enrichment of PRAME antigen‐specific T cells for adoptive immunotherapy using CD137 activation marker selection
OBJECTIVE: Adoptive immunotherapy with ex vivo expanded tumor‐specific T cells has potential as anticancer therapy. Preferentially expressed antigen in melanoma (PRAME) is an attractive target overexpressed in several cancers including melanoma and acute myeloid leukaemia (AML), with low expression...
Autores principales: | Lee, Koon H, Gowrishankar, Kavitha, Street, Janine, McGuire, Helen M, Luciani, Fabio, Hughes, Brendan, Singh, Mandeep, Clancy, Leighton E, Gottlieb, David J, Micklethwaite, Kenneth P, Blyth, Emily |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577233/ https://www.ncbi.nlm.nih.gov/pubmed/33101678 http://dx.doi.org/10.1002/cti2.1200 |
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