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Factors associated with malaria in indigenous populations: A retrospective study from 2007 to 2016

BACKGROUND: In Brazil malaria is most frequent in the Amazon region, mainly in the Amazonas state, where it is found the most proportion of indigenous people of the whole country. It is remarkable publications about malaria in the Amazon, although information on malaria in indigenous populations is...

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Autores principales: Meireles, Bruna Martins, de Souza Sampaio, Vanderson, Monteiro, Wuelton Marcelo, Gonçalves, Maria Jacirema Ferreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577477/
https://www.ncbi.nlm.nih.gov/pubmed/33085704
http://dx.doi.org/10.1371/journal.pone.0240741
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author Meireles, Bruna Martins
de Souza Sampaio, Vanderson
Monteiro, Wuelton Marcelo
Gonçalves, Maria Jacirema Ferreira
author_facet Meireles, Bruna Martins
de Souza Sampaio, Vanderson
Monteiro, Wuelton Marcelo
Gonçalves, Maria Jacirema Ferreira
author_sort Meireles, Bruna Martins
collection PubMed
description BACKGROUND: In Brazil malaria is most frequent in the Amazon region, mainly in the Amazonas state, where it is found the most proportion of indigenous people of the whole country. It is remarkable publications about malaria in the Amazon, although information on malaria in indigenous populations is still poorly explored. OBJECTIVE: Identify factors associated with malaria in indigenous populations. METHODS: Cross-sectional study of positive cases of malaria in the state of Amazonas, Brazil, from 2007 to 2016. Secondary data were obtained from the Epidemiological Surveillance Information System for Malaria and from the Mortality Information System, both from Brazil. To tackle with race missing data, cases with no race fulfilled were classified according to the probable location where infection occurred. This way, was imputed indigenous race for those which the probable infection location was indigenous village (aldeia). Variables tested with race were: sex, age, schooling, microscope surveillance slide type, parasitic infection species, parasitemia level, and timeliness of treatment. Multivariate logistic regression was used. RESULTS: A total of 1,055,852 cases of malaria were notified in the state of Amazonas. Among the factors that associate malaria and indigenous peoples, the most significant were sex, children and high levels of parasitemia. The magnitude of Plasmodium vivax infection is higher than Plasmodium falciparum, although this parasite was more frequent in indigenous than other races. In regards to mortality, 109 deaths were registered, most of them related to P. vivax. CONCLUSION: The findings underscore the importance of look at indigenous people differently of other races. The associated factors highlight a profile of cases severity, because of highest parasitemia, many cases of P. falciparum although high frequency of P. vivax, and children. Furthermore, the mortality in indigenous, specially in older people is worrying
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spelling pubmed-75774772020-10-26 Factors associated with malaria in indigenous populations: A retrospective study from 2007 to 2016 Meireles, Bruna Martins de Souza Sampaio, Vanderson Monteiro, Wuelton Marcelo Gonçalves, Maria Jacirema Ferreira PLoS One Research Article BACKGROUND: In Brazil malaria is most frequent in the Amazon region, mainly in the Amazonas state, where it is found the most proportion of indigenous people of the whole country. It is remarkable publications about malaria in the Amazon, although information on malaria in indigenous populations is still poorly explored. OBJECTIVE: Identify factors associated with malaria in indigenous populations. METHODS: Cross-sectional study of positive cases of malaria in the state of Amazonas, Brazil, from 2007 to 2016. Secondary data were obtained from the Epidemiological Surveillance Information System for Malaria and from the Mortality Information System, both from Brazil. To tackle with race missing data, cases with no race fulfilled were classified according to the probable location where infection occurred. This way, was imputed indigenous race for those which the probable infection location was indigenous village (aldeia). Variables tested with race were: sex, age, schooling, microscope surveillance slide type, parasitic infection species, parasitemia level, and timeliness of treatment. Multivariate logistic regression was used. RESULTS: A total of 1,055,852 cases of malaria were notified in the state of Amazonas. Among the factors that associate malaria and indigenous peoples, the most significant were sex, children and high levels of parasitemia. The magnitude of Plasmodium vivax infection is higher than Plasmodium falciparum, although this parasite was more frequent in indigenous than other races. In regards to mortality, 109 deaths were registered, most of them related to P. vivax. CONCLUSION: The findings underscore the importance of look at indigenous people differently of other races. The associated factors highlight a profile of cases severity, because of highest parasitemia, many cases of P. falciparum although high frequency of P. vivax, and children. Furthermore, the mortality in indigenous, specially in older people is worrying Public Library of Science 2020-10-21 /pmc/articles/PMC7577477/ /pubmed/33085704 http://dx.doi.org/10.1371/journal.pone.0240741 Text en © 2020 Meireles et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Meireles, Bruna Martins
de Souza Sampaio, Vanderson
Monteiro, Wuelton Marcelo
Gonçalves, Maria Jacirema Ferreira
Factors associated with malaria in indigenous populations: A retrospective study from 2007 to 2016
title Factors associated with malaria in indigenous populations: A retrospective study from 2007 to 2016
title_full Factors associated with malaria in indigenous populations: A retrospective study from 2007 to 2016
title_fullStr Factors associated with malaria in indigenous populations: A retrospective study from 2007 to 2016
title_full_unstemmed Factors associated with malaria in indigenous populations: A retrospective study from 2007 to 2016
title_short Factors associated with malaria in indigenous populations: A retrospective study from 2007 to 2016
title_sort factors associated with malaria in indigenous populations: a retrospective study from 2007 to 2016
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577477/
https://www.ncbi.nlm.nih.gov/pubmed/33085704
http://dx.doi.org/10.1371/journal.pone.0240741
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