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Transplant of Elderly Patients: Is There an Upper Age Cutoff?
Increased life expectancy and advances in the care of chronic liver disease has increased the number of elderly patients needing liver transplant. Organ donation policies prioritize transplant to the sickest. There is an ongoing debate with regard to balancing the principles of equity and utility. S...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577688/ https://www.ncbi.nlm.nih.gov/pubmed/33978580 http://dx.doi.org/10.1016/j.cld.2020.09.001 |
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author | Cottone, Claudia Pena Polanco, Nathalie A. Bhamidimarri, Kalyan Ram |
author_facet | Cottone, Claudia Pena Polanco, Nathalie A. Bhamidimarri, Kalyan Ram |
author_sort | Cottone, Claudia |
collection | PubMed |
description | Increased life expectancy and advances in the care of chronic liver disease has increased the number of elderly patients needing liver transplant. Organ donation policies prioritize transplant to the sickest. There is an ongoing debate with regard to balancing the principles of equity and utility. Several hospitals have adopted center-specific policies and there has been an increased trend of transplant in elderly patients since 2002. Appropriate patient selection and long-term outcomes in the setting of limited organ availability pose several challenges. This article reviews the data and discusses the pros and cons of transplants in the elderly. |
format | Online Article Text |
id | pubmed-7577688 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-75776882020-10-22 Transplant of Elderly Patients: Is There an Upper Age Cutoff? Cottone, Claudia Pena Polanco, Nathalie A. Bhamidimarri, Kalyan Ram Clin Liver Dis Article Increased life expectancy and advances in the care of chronic liver disease has increased the number of elderly patients needing liver transplant. Organ donation policies prioritize transplant to the sickest. There is an ongoing debate with regard to balancing the principles of equity and utility. Several hospitals have adopted center-specific policies and there has been an increased trend of transplant in elderly patients since 2002. Appropriate patient selection and long-term outcomes in the setting of limited organ availability pose several challenges. This article reviews the data and discusses the pros and cons of transplants in the elderly. Elsevier Inc. 2021-02 2020-10-21 /pmc/articles/PMC7577688/ /pubmed/33978580 http://dx.doi.org/10.1016/j.cld.2020.09.001 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Cottone, Claudia Pena Polanco, Nathalie A. Bhamidimarri, Kalyan Ram Transplant of Elderly Patients: Is There an Upper Age Cutoff? |
title | Transplant of Elderly Patients: Is There an Upper Age Cutoff? |
title_full | Transplant of Elderly Patients: Is There an Upper Age Cutoff? |
title_fullStr | Transplant of Elderly Patients: Is There an Upper Age Cutoff? |
title_full_unstemmed | Transplant of Elderly Patients: Is There an Upper Age Cutoff? |
title_short | Transplant of Elderly Patients: Is There an Upper Age Cutoff? |
title_sort | transplant of elderly patients: is there an upper age cutoff? |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577688/ https://www.ncbi.nlm.nih.gov/pubmed/33978580 http://dx.doi.org/10.1016/j.cld.2020.09.001 |
work_keys_str_mv | AT cottoneclaudia transplantofelderlypatientsisthereanupperagecutoff AT penapolanconathaliea transplantofelderlypatientsisthereanupperagecutoff AT bhamidimarrikalyanram transplantofelderlypatientsisthereanupperagecutoff |