CD1d1 intrinsic signaling in macrophages controls NLRP3 inflammasome expression during inflammation

Dysregulation of immune responses in the gut often associates with inflammatory bowel diseases (IBD). Mouse CD1d1, an ortholog of human CD1d mainly participating in lipid-antigen presentation to NKT cells, is able to generate intrinsic signals upon stimulation. Mice with macrophage-specific CD1d1 de...

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Detalles Bibliográficos
Autores principales: Cui, Shan, Wang, Chenhui, Bai, Weizhi, Li, Jiao, Pan, Yue, Huang, Xiaoyong, Yang, Han, Feng, Zeqing, Xiang, Qun, Fei, Lei, Zheng, Lixin, Huang, Jian, Zhang, Qinggao, Wu, Yuzhang, Chen, Yongwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577718/
https://www.ncbi.nlm.nih.gov/pubmed/33087357
http://dx.doi.org/10.1126/sciadv.aaz7290

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