The FAM171A2 gene is a key regulator of progranulin expression and modifies the risk of multiple neurodegenerative diseases

Progranulin (PGRN) is a secreted pleiotropic glycoprotein associated with the development of common neurodegenerative diseases. Understanding the pathophysiological role of PGRN may help uncover biological underpinnings. We performed a genome-wide association study to determine the genetic regulator...

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Detalles Bibliográficos
Autores principales: Xu, Wei, Han, Si-Da, Zhang, Can, Li, Jie-Qiong, Wang, Yan-Jiang, Tan, Chen-Chen, Li, Hong-Qi, Dong, Qiang, Mei, Cui, Tan, Lan, Yu, Jin-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577723/
https://www.ncbi.nlm.nih.gov/pubmed/33087363
http://dx.doi.org/10.1126/sciadv.abb3063

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