Decellularized extracellular matrix scaffolds identify full-length collagen VI as a driver of breast cancer cell invasion in obesity and metastasis

The extracellular matrix (ECM), a major component of the tumor microenvironment, promotes local invasion to drive metastasis. Here, we describe a method to study whole-tissue ECM effects from disease states associated with metastasis on tumor cell phenotypes and identify the individual ECM proteins...

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Detalles Bibliográficos
Autores principales: Wishart, Andrew L., Conner, Sydney J., Guarin, Justinne R., Fatherree, Jackson P., Peng, Yifan, McGinn, Rachel A., Crews, Rebecca, Naber, Stephen P., Hunter, Martin, Greenberg, Andrew S., Oudin, Madeleine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577726/
https://www.ncbi.nlm.nih.gov/pubmed/33087348
http://dx.doi.org/10.1126/sciadv.abc3175

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