Developmental, cellular, and behavioral phenotypes in a mouse model of congenital hypoplasia of the dentate gyrus

In the hippocampus, a widely accepted model posits that the dentate gyrus improves learning and memory by enhancing discrimination between inputs. To test this model, we studied conditional knockout mice in which the vast majority of dentate granule cells (DGCs) fail to develop – including nearly al...

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Detalles Bibliográficos
Autores principales: Rattner, Amir, Terrillion, Chantelle E, Jou, Claudia, Kleven, Tina, Hu, Shun Felix, Williams, John, Hou, Zhipeng, Aggarwal, Manisha, Mori, Susumu, Shin, Gloria, Goff, Loyal A, Witter, Menno P, Pletnikov, Mikhail, Fenton, André A, Nathans, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577738/
https://www.ncbi.nlm.nih.gov/pubmed/33084572
http://dx.doi.org/10.7554/eLife.62766

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