Cargando…
A Phase II Study of Avelumab Monotherapy in Patients with Mismatch Repair–Deficient/Microsatellite Instability–High or POLE-Mutated Metastatic or Unresectable Colorectal Cancer
PURPOSE: We evaluated the efficacy and safety of avelumab, an anti-PD-L1 antibody, in patients with metastatic or unresectable colorectal cancer (mCRC) with mismatch repair deficiency (dMMR)/microsatellite instability-high (MSI-H) or POLE mutations. MATERIALS AND METHODS: In this prospective, open-l...
Autores principales: | Kim, Jwa Hoon, Kim, Sun Young, Baek, Ji Yeon, Cha, Yong Jun, Ahn, Joong Bae, Kim, Han Sang, Lee, Keun-Wook, Kim, Ji-Won, Kim, Tae-You, Chang, Won Jin, Park, Joon Oh, Kim, Jihun, Kim, Jeong Eun, Hong, Yong Sang, Kim, Yeul Hong, Kim, Tae Won |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Cancer Association
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577804/ https://www.ncbi.nlm.nih.gov/pubmed/32340084 http://dx.doi.org/10.4143/crt.2020.218 |
Ejemplares similares
-
Histopathologic and Molecular Biomarkers of PD-1/PD-L1 Inhibitor Treatment Response among Patients with Microsatellite Instability–High Colon Cancer
por: Hyung, Jaewon, et al.
Publicado: (2022) -
Adjuvant Chemotherapy in Microsatellite Instability–High Gastric Cancer
por: Kim, Jin Won, et al.
Publicado: (2020) -
Clinical Significance of Microsatellite Instability in Sporadic Epithelial Ovarian Tumors
por: Yoon, Bo-Sung, et al.
Publicado: (2008) -
Twist1-induced epithelial-mesenchymal transition according to microsatellite instability status in colon cancer cells
por: Oh, Bo Young, et al.
Publicado: (2016) -
Outcomes of concurrent chemoradiotherapy versus chemotherapy alone for advanced-stage unresectable intrahepatic cholangiocarcinoma
por: Kim, Young-Il, et al.
Publicado: (2013)