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Loss of PRCD alters number and packaging density of rhodopsin in rod photoreceptor disc membranes

Progressive rod-cone degeneration (PRCD) is a small protein localized to photoreceptor outer segment (OS) disc membranes. Several mutations in PRCD are linked to retinitis pigmentosa (RP) in canines and humans, and while recent studies have established that PRCD is required for high fidelity disc mo...

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Detalles Bibliográficos
Autores principales:	Sechrest, Emily R., Murphy, Joseph, Senapati, Subhadip, Goldberg, Andrew F. X., Park, Paul S.-H., Kolandaivelu, Saravanan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577997/ https://www.ncbi.nlm.nih.gov/pubmed/33087780 http://dx.doi.org/10.1038/s41598-020-74628-2

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