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TBC1D1 interacting proteins, VPS13A and VPS13C, regulate GLUT4 homeostasis in C2C12 myotubes
Proteins involved in the spaciotemporal regulation of GLUT4 trafficking represent potential therapeutic targets for the treatment of insulin resistance and type 2 diabetes. A key regulator of insulin- and exercise-stimulated glucose uptake and GLUT4 trafficking is TBC1D1. This study aimed to identif...
Autores principales: | Hook, Sharon C., Chadt, Alexandra, Heesom, Kate J., Kishida, Shosei, Al-Hasani, Hadi, Tavaré, Jeremy M., Thomas, Elaine C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578007/ https://www.ncbi.nlm.nih.gov/pubmed/33087848 http://dx.doi.org/10.1038/s41598-020-74661-1 |
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