Cargando…

RPN2 is targeted by miR-181c and mediates glioma progression and temozolomide sensitivity via the wnt/β-catenin signaling pathway

Accumulating evidence indicates that the dysregulation of the miRNAs/mRNA-mediated carcinogenic signaling pathway network is intimately involved in glioma initiation and progression. In the present study, by performing experiments and bioinformatics analysis, we found that RPN2 was markedly elevated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Jikui, Ma, Quanfeng, Li, Banban, Wang, Chen, Mo, Lidong, Zhang, Xuebin, Tang, Fan, Wang, Qiong, Yan, Xiaoling, Yao, Xiuhua, Wu, Qiaoli, Shu, Chang, Xiong, Jinbiao, Fan, Weijia, Wang, Jinhuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578010/ https://www.ncbi.nlm.nih.gov/pubmed/33087705 http://dx.doi.org/10.1038/s41419-020-03113-5

Ejemplares similares

MicroRNA-422a functions as a tumor suppressor in glioma by regulating the Wnt/β-catenin signaling pathway via RPN2
por: Sun, Jikui, et al.
Publicado: (2020)

MicroRNA-301a/ZNRF3/wnt/β-catenin signal regulatory crosstalk mediates glioma progression
por: Sun, Jikui, et al.
Publicado: (2020)

Functions and clinical significance of circular RNAs in glioma
por: Sun, Jikui, et al.
Publicado: (2020)

circTOP2A functions as a ceRNA to promote glioma progression by upregulating RPN2
por: Sun, Jikui, et al.
Publicado: (2022)

MiR-19 regulates the proliferation and invasion of glioma by RUNX3 via β-catenin/Tcf-4 signaling
por: Sun, Jikui, et al.
Publicado: (2017)

Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma
por: Ji, Junfang, et al.
Publicado: (2011)

MicroRNA-139-5p/Flt1/Wnt/β-catenin regulatory crosstalk modulates the progression of glioma
por: Wang, Qiong, et al.
Publicado: (2018)

Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets
por: Lu, Xiuxiu, et al.
Publicado: (2017)

UBE2T Promotes Temozolomide Resistance of Glioblastoma Through Regulating the Wnt/β-Catenin Signaling Pathway
por: Wang, Yang, et al.
Publicado: (2023)

Structure of Rpn10 and Its Interactions with Polyubiquitin Chains and the Proteasome Subunit Rpn12
por: Riedinger, Christiane, et al.
Publicado: (2010)

Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis
por: Hamazaki, Jun, et al.
Publicado: (2015)

Structural and functional characterization of Rpn12 identifies residues required for Rpn10 proteasome incorporation
por: Boehringer, Jonas, et al.
Publicado: (2012)

Wnt/β-catenin signaling pathway induces autophagy-mediated temozolomide-resistance in human glioblastoma
por: Yun, Eun-Jin, et al.
Publicado: (2020)

MiR-181b suppresses proliferation of and reduces chemoresistance to temozolomide in U87 glioma stem cells()
por: Li, Ping, et al.
Publicado: (2010)

Lichen Secondary Metabolites Inhibit the Wnt/β-Catenin Pathway in Glioblastoma Cells and Improve the Anticancer Effects of Temozolomide
por: Majchrzak-Celińska, Aleksandra, et al.
Publicado: (2022)

Wnt/β-catenin signaling may induce senescence of chondrocytes in osteoarthritis
por: Li, Weijun, et al.
Publicado: (2020)

A High Affinity hRpn2-Derived Peptide That Displaces Human Rpn13 from Proteasome in 293T Cells
por: Lu, Xiuxiu, et al.
Publicado: (2015)

HMGN5 Silencing Suppresses Cell Biological Progression via AKT/MAPK Pathway in Human Glioblastoma Cells
por: Ma, Quanfeng, et al.
Publicado: (2020)

A positive feedback loop of lncRNA-RMRP/ZNRF3 axis and Wnt/β-catenin signaling regulates the progression and temozolomide resistance in glioma
por: Liu, Tie, et al.
Publicado: (2021)

Mechanism of the Rpn13-induced activation of Uch37
por: Jiao, Lianying, et al.
Publicado: (2014)

Pyrvinium pamoate regulates MGMT expression through suppressing the Wnt/β-catenin signaling pathway to enhance the glioblastoma sensitivity to temozolomide
por: Li, Haisong, et al.
Publicado: (2021)

The silencing of LncRNA-H19 decreases chemoresistance of human glioma cells to temozolomide by suppressing epithelial-mesenchymal transition via the Wnt/β-Catenin pathway
por: Jia, Linwei, et al.
Publicado: (2018)

Study on ZmRPN10 Regulating Leaf Angle in Maize by RNA-Seq
por: Ji, Xiangzhuo, et al.
Publicado: (2022)

Wnt/β-Catenin Signaling and Obesity
por: Chen, Na, et al.
Publicado: (2018)

Inhibition of canonical WNT/β-catenin signaling is involved in leflunomide (LEF)-mediated cytotoxic effects on renal carcinoma cells
por: Chen, Yicheng, et al.
Publicado: (2016)

Opposing roles of ICAT and Wnt/β-catenin signaling in NSC67657-induced monocytic differentiation
por: Wang, Weijia, et al.
Publicado: (2017)

TMT-based proteomics analysis of the cerebral cortex of TauT knockout rats
por: Xia, Yiming, et al.
Publicado: (2022)

Covalent Rpn13-Binding Inhibitors for the Treatment of Ovarian Cancer
por: Anchoori, Ravi K., et al.
Publicado: (2018)

Spillover effect among independent carbon markets: evidence from China’s carbon markets
por: Yan, Yaxue, et al.
Publicado: (2022)

LncRNA CARLo-7 facilitates proliferation, migration, invasion, and EMT of bladder cancer cells by regulating Wnt/β-catenin and JAK2/STAT3 signaling pathways
por: Huang, Houfeng, et al.
Publicado: (2020)

The Silencing of LncRNA-H19 Decreases Chemoresistance of Human Glioma Cells to Temozolomide by Suppressing Epithelial-Mesenchymal Transition via the Wnt/β-Catenin Pathway [Retraction]
Publicado: (2022)

Trichosanthin suppresses the proliferation of glioma cells by inhibiting LGR5 expression and the Wnt/β-catenin signaling pathway
por: MIAO, JUNJIE, et al.
Publicado: (2015)

Overexpression of RPN2 suppresses radiosensitivity of glioma cells by activating STAT3 signal transduction
por: Li, Changyu, et al.
Publicado: (2020)

NOVA1 promotes NSCLC proliferation and invasion by activating Wnt/β-catenin signaling
por: Qu, Lianyue, et al.
Publicado: (2022)

RTL1 promotes melanoma proliferation by regulating Wnt/β-catenin signalling
por: Fan, Guobiao, et al.
Publicado: (2017)

Structure-function analyses of candidate small molecule RPN13 inhibitors with antitumor properties
por: Anchoori, Ravi K., et al.
Publicado: (2020)

Rotavirus-Mediated Suppression of miRNA-192 Family and miRNA-181a Activates Wnt/β-Catenin Signaling Pathway: An In Vitro Study
por: Banerjee, Anwesha, et al.
Publicado: (2022)

Wnt/β-catenin and Hedgehog pathways are involved in the inflammatory effect of Interleukin 18 on rat chondrocytes
por: Bao, Jiapeng, et al.
Publicado: (2017)

β-catenin is overexpressed in hepatic fibrosis and blockage of Wnt/β-catenin signaling inhibits hepatic stellate cell activation
por: GE, WEN-SONG, et al.
Publicado: (2014)

Roles of Wnt/β-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment
por: Mao, J, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_h809ejsq6jn0b9a1u3k76s5s99