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Mechanisms of interleukin 4 mediated increase in efficacy of vaccines against opioid use disorders

Opioid use disorders (OUD) affect over 27 million people worldwide. Anti-opioid vaccines offer a promising strategy to treat OUD and prevent overdose. Using immunomodulation of cytokine signaling to increase vaccine efficacy, this study found that blocking IL-4 improved the efficacy of vaccines targ...

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Detalles Bibliográficos
Autores principales:	Crouse, Bethany, Robinson, Christine, Huseby Kelcher, April, Laudenbach, Megan, Abrahante, Juan E., Pravetoni, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578047/ https://www.ncbi.nlm.nih.gov/pubmed/33101712 http://dx.doi.org/10.1038/s41541-020-00247-7

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