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Interleukin-33 activates regulatory T cells to suppress innate γδ T cell responses in the lung

Foxp3(+) regulatory T (T(reg)) cells expressing the interleukin (IL)-33 receptor ST2 mediate tissue repair in response to IL-33. Whether T(reg) cells also respond to the alarmin IL-33 to regulate specific aspects of the immune response is not known. Here we describe an unexpected function of ST2(+)...

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Detalles Bibliográficos
Autores principales:	Faustino, Lucas D., Griffith, Jason W., Rahimi, Rod A., Nepal, Keshav, Hamilos, Daniel L., Cho, Josalyn L., Medoff, Benjamin D., Moon, James J., Vignali, Dario A.A., Luster, Andrew D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578082/ https://www.ncbi.nlm.nih.gov/pubmed/32989331 http://dx.doi.org/10.1038/s41590-020-0785-3

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