Strength of tonic T cell receptor signaling instructs T follicular helper fate decisions

T follicular helper (Tfh) cells are critical in adaptive immune responses to pathogens and vaccines; however, what drives initiation of their developmental program remains unclear. Studies suggest a T cell antigen receptor (TCR)-dependent mechanism may be responsible for the earliest Tfh-fate decisi...

Descripción completa

Detalles Bibliográficos
Autores principales: Bartleson, Juliet M., Milam, Ashley A. Viehmann, Donermeyer, David L., Horvath, Stephen, Xia, Yu, Egawa, Takeshi, Allen, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578106/
https://www.ncbi.nlm.nih.gov/pubmed/32989327
http://dx.doi.org/10.1038/s41590-020-0781-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578106/
https://www.ncbi.nlm.nih.gov/pubmed/32989327
http://dx.doi.org/10.1038/s41590-020-0781-7

Ejemplares similares