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Strength of tonic T cell receptor signaling instructs T follicular helper fate decisions
T follicular helper (Tfh) cells are critical in adaptive immune responses to pathogens and vaccines; however, what drives initiation of their developmental program remains unclear. Studies suggest a T cell antigen receptor (TCR)-dependent mechanism may be responsible for the earliest Tfh-fate decisi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578106/ https://www.ncbi.nlm.nih.gov/pubmed/32989327 http://dx.doi.org/10.1038/s41590-020-0781-7 |