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Detection of EGFR Mutations in cfDNA and CTCs, and Comparison to Tumor Tissue in Non-Small-Cell-Lung-Cancer (NSCLC) Patients

Lung cancer is the leading cause of cancer-related mortality worldwide. Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) therapies, based on the evaluation of EGFR mutations, have shown dramatic clinical benefits. EGFR mutation assays are mainly performed on tumor biopsies, wh...

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Detalles Bibliográficos
Autores principales: Liu, Haiyan E., Vuppalapaty, Meghah, Wilkerson, Charles, Renier, Corinne, Chiu, Michael, Lemaire, Clementine, Che, James, Matsumoto, Melissa, Carroll, James, Crouse, Steve, Hanft, Violet R., Jeffrey, Stefanie S., Di Carlo, Dino, Garon, Edward B., Goldman, Jonathan, Sollier, Elodie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578230/
https://www.ncbi.nlm.nih.gov/pubmed/33117705
http://dx.doi.org/10.3389/fonc.2020.572895