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Anti-cancer strategy targeting the energy metabolism of tumor cells surviving a low-nutrient acidic microenvironment

OBJECTIVE: Tumor cells experience hypoxia, acidosis, and hypoglycemia. Metabolic adaptation to glucose shortage is essential to maintain tumor cells’ survival because of their high glucose requirement. This study evaluated the hypothesis that acidosis might promote tumor survival during glucose shor...

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Detalles Bibliográficos
Autores principales:	Maeda, Yuki, Kikuchi, Ryota, Kawagoe, Junichiro, Tsuji, Takao, Koyama, Nobuyuki, Yamaguchi, Kazuhiro, Nakamura, Hiroyuki, Aoshiba, Kazutetsu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578269/ https://www.ncbi.nlm.nih.gov/pubmed/33007425 http://dx.doi.org/10.1016/j.molmet.2020.101093

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