Cargando…

Retrospective study on symptoms and treatment modalities used and short‐term follow up of achalasia cardia in Indian setting

BACKGROUND: Achalasia cardia is a rare esophageal motor disorder that is frequently diagnosed late. AIM: The aim of this study was to study the symptoms, treatment given, and response to treatment in patients with achalasia cardia in an Indian setting. MATERIALS AND METHODS: This retrospective study...

Descripción completa

Detalles Bibliográficos
Autores principales: Jain, Mayank, Baijal, Neha, Srinivas, Melpakkam, Baijal, Rajiv, Pratap, Nitesh, Bachkaniwala, Vatsal, Ganesh, P, Venkataraman, Jayanthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Publishing Asia Pty Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578270/
https://www.ncbi.nlm.nih.gov/pubmed/33102755
http://dx.doi.org/10.1002/jgh3.12328
_version_ 1783598328179589120
author Jain, Mayank
Baijal, Neha
Srinivas, Melpakkam
Baijal, Rajiv
Pratap, Nitesh
Bachkaniwala, Vatsal
Ganesh, P
Venkataraman, Jayanthi
author_facet Jain, Mayank
Baijal, Neha
Srinivas, Melpakkam
Baijal, Rajiv
Pratap, Nitesh
Bachkaniwala, Vatsal
Ganesh, P
Venkataraman, Jayanthi
author_sort Jain, Mayank
collection PubMed
description BACKGROUND: Achalasia cardia is a rare esophageal motor disorder that is frequently diagnosed late. AIM: The aim of this study was to study the symptoms, treatment given, and response to treatment in patients with achalasia cardia in an Indian setting. MATERIALS AND METHODS: This retrospective study included all patients diagnosed with achalasia cardia on high‐resolution esophageal manometry, using Chicago Classification v 3.0. On follow up, patients were contacted by telephone, and details of the treatment given and response were recorded in a predesigned pro forma. We excluded overseas patients, postoperative cases of achalasia, and those in whom the manometry catheter could not be passed across the gastroesophageal junction. RESULTS: A total of 452 patients (260 males, median age 44.5 years) were included in the study cohort. The major symptoms included dysphagia for solids and liquids (428, 94.7%), regurgitation (360, 79.6%), naso‐oral regurgitation (182, 40.3%), weight loss (322, 71.3%), and chest pain (158, 35%). Type 2 achalasia (229, 50.6%) was the most common subtype, followed by type 3 (154, 34.1%). Chest pain was more common in type 3, and weight loss and naso‐oral regurgitation were more common in type 2 achalasia. A majority of patients underwent Heller's myotomy and pneumatic dilatation. Of 280 patients for whom treatment details were available, 98% reported good response to endoscopic/surgical management. CONCLUSION: The predominant symptoms of achalasia cardia vary per the manometric subtype. Heller's myotomy and pneumatic dilatation are the most commonly used treatment options. Response to treatment is good. The choice of treatment modality was likely influenced by financial reasons and availability of local expertise.
format Online
Article
Text
id pubmed-7578270
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Wiley Publishing Asia Pty Ltd
record_format MEDLINE/PubMed
spelling pubmed-75782702020-10-23 Retrospective study on symptoms and treatment modalities used and short‐term follow up of achalasia cardia in Indian setting Jain, Mayank Baijal, Neha Srinivas, Melpakkam Baijal, Rajiv Pratap, Nitesh Bachkaniwala, Vatsal Ganesh, P Venkataraman, Jayanthi JGH Open Original Articles BACKGROUND: Achalasia cardia is a rare esophageal motor disorder that is frequently diagnosed late. AIM: The aim of this study was to study the symptoms, treatment given, and response to treatment in patients with achalasia cardia in an Indian setting. MATERIALS AND METHODS: This retrospective study included all patients diagnosed with achalasia cardia on high‐resolution esophageal manometry, using Chicago Classification v 3.0. On follow up, patients were contacted by telephone, and details of the treatment given and response were recorded in a predesigned pro forma. We excluded overseas patients, postoperative cases of achalasia, and those in whom the manometry catheter could not be passed across the gastroesophageal junction. RESULTS: A total of 452 patients (260 males, median age 44.5 years) were included in the study cohort. The major symptoms included dysphagia for solids and liquids (428, 94.7%), regurgitation (360, 79.6%), naso‐oral regurgitation (182, 40.3%), weight loss (322, 71.3%), and chest pain (158, 35%). Type 2 achalasia (229, 50.6%) was the most common subtype, followed by type 3 (154, 34.1%). Chest pain was more common in type 3, and weight loss and naso‐oral regurgitation were more common in type 2 achalasia. A majority of patients underwent Heller's myotomy and pneumatic dilatation. Of 280 patients for whom treatment details were available, 98% reported good response to endoscopic/surgical management. CONCLUSION: The predominant symptoms of achalasia cardia vary per the manometric subtype. Heller's myotomy and pneumatic dilatation are the most commonly used treatment options. Response to treatment is good. The choice of treatment modality was likely influenced by financial reasons and availability of local expertise. Wiley Publishing Asia Pty Ltd 2020-03-24 /pmc/articles/PMC7578270/ /pubmed/33102755 http://dx.doi.org/10.1002/jgh3.12328 Text en © 2020 The Authors. JGH Open: An open access journal of gastroenterology and hepatology published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Jain, Mayank
Baijal, Neha
Srinivas, Melpakkam
Baijal, Rajiv
Pratap, Nitesh
Bachkaniwala, Vatsal
Ganesh, P
Venkataraman, Jayanthi
Retrospective study on symptoms and treatment modalities used and short‐term follow up of achalasia cardia in Indian setting
title Retrospective study on symptoms and treatment modalities used and short‐term follow up of achalasia cardia in Indian setting
title_full Retrospective study on symptoms and treatment modalities used and short‐term follow up of achalasia cardia in Indian setting
title_fullStr Retrospective study on symptoms and treatment modalities used and short‐term follow up of achalasia cardia in Indian setting
title_full_unstemmed Retrospective study on symptoms and treatment modalities used and short‐term follow up of achalasia cardia in Indian setting
title_short Retrospective study on symptoms and treatment modalities used and short‐term follow up of achalasia cardia in Indian setting
title_sort retrospective study on symptoms and treatment modalities used and short‐term follow up of achalasia cardia in indian setting
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578270/
https://www.ncbi.nlm.nih.gov/pubmed/33102755
http://dx.doi.org/10.1002/jgh3.12328
work_keys_str_mv AT jainmayank retrospectivestudyonsymptomsandtreatmentmodalitiesusedandshorttermfollowupofachalasiacardiainindiansetting
AT baijalneha retrospectivestudyonsymptomsandtreatmentmodalitiesusedandshorttermfollowupofachalasiacardiainindiansetting
AT srinivasmelpakkam retrospectivestudyonsymptomsandtreatmentmodalitiesusedandshorttermfollowupofachalasiacardiainindiansetting
AT baijalrajiv retrospectivestudyonsymptomsandtreatmentmodalitiesusedandshorttermfollowupofachalasiacardiainindiansetting
AT pratapnitesh retrospectivestudyonsymptomsandtreatmentmodalitiesusedandshorttermfollowupofachalasiacardiainindiansetting
AT bachkaniwalavatsal retrospectivestudyonsymptomsandtreatmentmodalitiesusedandshorttermfollowupofachalasiacardiainindiansetting
AT ganeshp retrospectivestudyonsymptomsandtreatmentmodalitiesusedandshorttermfollowupofachalasiacardiainindiansetting
AT venkataramanjayanthi retrospectivestudyonsymptomsandtreatmentmodalitiesusedandshorttermfollowupofachalasiacardiainindiansetting