Cargando…
Retrospective study on symptoms and treatment modalities used and short‐term follow up of achalasia cardia in Indian setting
BACKGROUND: Achalasia cardia is a rare esophageal motor disorder that is frequently diagnosed late. AIM: The aim of this study was to study the symptoms, treatment given, and response to treatment in patients with achalasia cardia in an Indian setting. MATERIALS AND METHODS: This retrospective study...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Publishing Asia Pty Ltd
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578270/ https://www.ncbi.nlm.nih.gov/pubmed/33102755 http://dx.doi.org/10.1002/jgh3.12328 |
_version_ | 1783598328179589120 |
---|---|
author | Jain, Mayank Baijal, Neha Srinivas, Melpakkam Baijal, Rajiv Pratap, Nitesh Bachkaniwala, Vatsal Ganesh, P Venkataraman, Jayanthi |
author_facet | Jain, Mayank Baijal, Neha Srinivas, Melpakkam Baijal, Rajiv Pratap, Nitesh Bachkaniwala, Vatsal Ganesh, P Venkataraman, Jayanthi |
author_sort | Jain, Mayank |
collection | PubMed |
description | BACKGROUND: Achalasia cardia is a rare esophageal motor disorder that is frequently diagnosed late. AIM: The aim of this study was to study the symptoms, treatment given, and response to treatment in patients with achalasia cardia in an Indian setting. MATERIALS AND METHODS: This retrospective study included all patients diagnosed with achalasia cardia on high‐resolution esophageal manometry, using Chicago Classification v 3.0. On follow up, patients were contacted by telephone, and details of the treatment given and response were recorded in a predesigned pro forma. We excluded overseas patients, postoperative cases of achalasia, and those in whom the manometry catheter could not be passed across the gastroesophageal junction. RESULTS: A total of 452 patients (260 males, median age 44.5 years) were included in the study cohort. The major symptoms included dysphagia for solids and liquids (428, 94.7%), regurgitation (360, 79.6%), naso‐oral regurgitation (182, 40.3%), weight loss (322, 71.3%), and chest pain (158, 35%). Type 2 achalasia (229, 50.6%) was the most common subtype, followed by type 3 (154, 34.1%). Chest pain was more common in type 3, and weight loss and naso‐oral regurgitation were more common in type 2 achalasia. A majority of patients underwent Heller's myotomy and pneumatic dilatation. Of 280 patients for whom treatment details were available, 98% reported good response to endoscopic/surgical management. CONCLUSION: The predominant symptoms of achalasia cardia vary per the manometric subtype. Heller's myotomy and pneumatic dilatation are the most commonly used treatment options. Response to treatment is good. The choice of treatment modality was likely influenced by financial reasons and availability of local expertise. |
format | Online Article Text |
id | pubmed-7578270 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wiley Publishing Asia Pty Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-75782702020-10-23 Retrospective study on symptoms and treatment modalities used and short‐term follow up of achalasia cardia in Indian setting Jain, Mayank Baijal, Neha Srinivas, Melpakkam Baijal, Rajiv Pratap, Nitesh Bachkaniwala, Vatsal Ganesh, P Venkataraman, Jayanthi JGH Open Original Articles BACKGROUND: Achalasia cardia is a rare esophageal motor disorder that is frequently diagnosed late. AIM: The aim of this study was to study the symptoms, treatment given, and response to treatment in patients with achalasia cardia in an Indian setting. MATERIALS AND METHODS: This retrospective study included all patients diagnosed with achalasia cardia on high‐resolution esophageal manometry, using Chicago Classification v 3.0. On follow up, patients were contacted by telephone, and details of the treatment given and response were recorded in a predesigned pro forma. We excluded overseas patients, postoperative cases of achalasia, and those in whom the manometry catheter could not be passed across the gastroesophageal junction. RESULTS: A total of 452 patients (260 males, median age 44.5 years) were included in the study cohort. The major symptoms included dysphagia for solids and liquids (428, 94.7%), regurgitation (360, 79.6%), naso‐oral regurgitation (182, 40.3%), weight loss (322, 71.3%), and chest pain (158, 35%). Type 2 achalasia (229, 50.6%) was the most common subtype, followed by type 3 (154, 34.1%). Chest pain was more common in type 3, and weight loss and naso‐oral regurgitation were more common in type 2 achalasia. A majority of patients underwent Heller's myotomy and pneumatic dilatation. Of 280 patients for whom treatment details were available, 98% reported good response to endoscopic/surgical management. CONCLUSION: The predominant symptoms of achalasia cardia vary per the manometric subtype. Heller's myotomy and pneumatic dilatation are the most commonly used treatment options. Response to treatment is good. The choice of treatment modality was likely influenced by financial reasons and availability of local expertise. Wiley Publishing Asia Pty Ltd 2020-03-24 /pmc/articles/PMC7578270/ /pubmed/33102755 http://dx.doi.org/10.1002/jgh3.12328 Text en © 2020 The Authors. JGH Open: An open access journal of gastroenterology and hepatology published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Original Articles Jain, Mayank Baijal, Neha Srinivas, Melpakkam Baijal, Rajiv Pratap, Nitesh Bachkaniwala, Vatsal Ganesh, P Venkataraman, Jayanthi Retrospective study on symptoms and treatment modalities used and short‐term follow up of achalasia cardia in Indian setting |
title | Retrospective study on symptoms and treatment modalities used and short‐term follow up of achalasia cardia in Indian setting |
title_full | Retrospective study on symptoms and treatment modalities used and short‐term follow up of achalasia cardia in Indian setting |
title_fullStr | Retrospective study on symptoms and treatment modalities used and short‐term follow up of achalasia cardia in Indian setting |
title_full_unstemmed | Retrospective study on symptoms and treatment modalities used and short‐term follow up of achalasia cardia in Indian setting |
title_short | Retrospective study on symptoms and treatment modalities used and short‐term follow up of achalasia cardia in Indian setting |
title_sort | retrospective study on symptoms and treatment modalities used and short‐term follow up of achalasia cardia in indian setting |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578270/ https://www.ncbi.nlm.nih.gov/pubmed/33102755 http://dx.doi.org/10.1002/jgh3.12328 |
work_keys_str_mv | AT jainmayank retrospectivestudyonsymptomsandtreatmentmodalitiesusedandshorttermfollowupofachalasiacardiainindiansetting AT baijalneha retrospectivestudyonsymptomsandtreatmentmodalitiesusedandshorttermfollowupofachalasiacardiainindiansetting AT srinivasmelpakkam retrospectivestudyonsymptomsandtreatmentmodalitiesusedandshorttermfollowupofachalasiacardiainindiansetting AT baijalrajiv retrospectivestudyonsymptomsandtreatmentmodalitiesusedandshorttermfollowupofachalasiacardiainindiansetting AT pratapnitesh retrospectivestudyonsymptomsandtreatmentmodalitiesusedandshorttermfollowupofachalasiacardiainindiansetting AT bachkaniwalavatsal retrospectivestudyonsymptomsandtreatmentmodalitiesusedandshorttermfollowupofachalasiacardiainindiansetting AT ganeshp retrospectivestudyonsymptomsandtreatmentmodalitiesusedandshorttermfollowupofachalasiacardiainindiansetting AT venkataramanjayanthi retrospectivestudyonsymptomsandtreatmentmodalitiesusedandshorttermfollowupofachalasiacardiainindiansetting |