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Viral burden, inflammatory milieu and CD8(+) T‐cell responses to influenza virus in a second‐generation thiazolide (RM‐5061) and oseltamivir combination therapy study

BACKGROUND: Influenza viruses cause significant morbidity and mortality, especially in young children, elderly, pregnant women and individuals with co‐morbidities. Patients with severe influenza disease are typically treated with one neuraminidase inhibitor, oseltamivir or zanamivir. These antiviral...

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Detalles Bibliográficos
Autores principales: Nüssing, Simone, Mifsud, Edin, Hensen, Luca, Koutsakos, Marios, Wang, Zhongfang, Kedzierski, Lukasz, Mercuri, Francesca, Rossignol, Jean‐Francois, Hurt, Aeron C., Kedzierska, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578329/
https://www.ncbi.nlm.nih.gov/pubmed/32588557
http://dx.doi.org/10.1111/irv.12776