The SDHB Arg230His mutation causing familial paraganglioma alters glycolysis in a new Caenorhabditis elegans model

The conserved B-subunit of succinate dehydrogenase (SDH) participates in the tricarboxylic acid cycle (TCA) cycle and mitochondrial electron transport. The Arg230His mutation in SDHB causes heritable pheochromocytoma/paraganglioma (PPGL). In Caenorhabditis elegans, we generated an in vivo PPGL model...

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Detalles Bibliográficos
Autores principales: Saskői, Éva, Hujber, Zoltán, Nyírő, Gábor, Likó, István, Mátyási, Barbara, Petővári, Gábor, Mészáros, Katalin, Kovács, Attila L., Patthy, László, Supekar, Shreyas, Fan, Hao, Sváb, Gergely, Tretter, László, Sarkar, Arunabh, Nazir, Aamir, Sebestyén, Anna, Patócs, Attila, Mehta, Anil, Takács-Vellai, Krisztina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578352/
https://www.ncbi.nlm.nih.gov/pubmed/32859697
http://dx.doi.org/10.1242/dmm.044925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578352/
https://www.ncbi.nlm.nih.gov/pubmed/32859697
http://dx.doi.org/10.1242/dmm.044925

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