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Rapid in silico Design of Potential Cyclic Peptide Binders Targeting Protein-Protein Interfaces

Rational design of specific inhibitors of protein-protein interactions is desirable for drug design to control cellular signal transduction but also for studying protein-protein interaction networks. We have developed a rapid computational approach to rationally design cyclic peptides that potential...

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Detalles Bibliográficos
Autores principales: Santini, Brianda L., Zacharias, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578414/
https://www.ncbi.nlm.nih.gov/pubmed/33134275
http://dx.doi.org/10.3389/fchem.2020.573259