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Intrinsic Restriction of TNF-Mediated Inflammatory Osteoclastogenesis and Bone Resorption

TNF (Tumor necrosis factor) is a pleiotropic cytokine that plays an important role in immunity and inflammatory bone destruction. Homeostatic osteoclastogenesis is effectively induced by RANKL (Receptor activator of nuclear factor kappa-B ligand). In contrast, TNF often acts on cell types other than...

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Detalles Bibliográficos
Autor principal: Zhao, Baohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578415/
https://www.ncbi.nlm.nih.gov/pubmed/33133025
http://dx.doi.org/10.3389/fendo.2020.583561

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