Cargando…

PPARα Ameliorates Doxorubicin-Induced Cardiotoxicity by Reducing Mitochondria-Dependent Apoptosis via Regulating MEOX1

Doxorubicin (DOX), a chemotherapeutic drug widely used in the clinical setting, is known to cause serious cardiotoxicity and greatly reduces the survival rate as well as quality of life of patients receiving chemotherapy. Peroxisome proliferation activated receptor α (PPARα) is a type of ligand acti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Wei, Fang, Qin, Zhang, Zhihao, Wang, Daowen, Wu, Lujin, Wang, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578427/ https://www.ncbi.nlm.nih.gov/pubmed/33132907 http://dx.doi.org/10.3389/fphar.2020.528267

Ejemplares similares

Dimethyl Fumarate Ameliorates Doxorubicin-Induced Cardiotoxicity By Activating the Nrf2 Pathway
por: Hu, Xiaoliang, et al.
Publicado: (2022)

Bibliometric and visual analysis of doxorubicin-induced cardiotoxicity
por: Lin, Xiaoxiao, et al.
Publicado: (2023)

Heat Shock Protein 22 Attenuates Doxorubicin-Induced Cardiotoxicity via Regulating Inflammation and Apoptosis
por: Lan, Yin, et al.
Publicado: (2020)

Oleoylethanolamide as a New Therapeutic Strategy to Alleviate Doxorubicin-Induced Cardiotoxicity
por: Qin, Yeyu, et al.
Publicado: (2022)

Combat Doxorubicin Cardiotoxicity With the Power of Mitochondria Transfer
por: Wang, Dennis D., et al.
Publicado: (2021)

Danhong injection attenuates doxorubicin-induced cardiotoxicity in rats via suppression of apoptosis: network pharmacology analysis and experimental validation
por: Yi, Xiaojiao, et al.
Publicado: (2022)

PPARα ligand, AVE8134, and cyclooxygenase inhibitor therapy synergistically suppress lung cancer growth and metastasis
por: Wu, Lujin, et al.
Publicado: (2019)

Setanaxib (GKT137831) Ameliorates Doxorubicin-Induced Cardiotoxicity by Inhibiting the NOX1/NOX4/Reactive Oxygen Species/MAPK Pathway
por: Zheng, Hui, et al.
Publicado: (2022)

Chrysanthemum morifolium Extract Ameliorates Doxorubicin-Induced Cardiotoxicity by Decreasing Apoptosis
por: Ono, Masaya, et al.
Publicado: (2022)

Dipyridamole ameliorates doxorubicin-induced cardiotoxicity
por: Alyasiry, Esraa, et al.
Publicado: (2022)

Cardioprotective Roles of β-Hydroxybutyrate Against Doxorubicin Induced Cardiotoxicity
por: Liu, Yihai, et al.
Publicado: (2021)

MicroRNAs in doxorubicin-induced cardiotoxicity: The DNA damage response
por: Kawano, Ippei, et al.
Publicado: (2022)

SIRT1 activation and its effect on intercalated disc proteins as a way to reduce doxorubicin cardiotoxicity
por: Podyacheva, Ekaterina, et al.
Publicado: (2022)

Tripartite motif 25 ameliorates doxorubicin-induced cardiotoxicity by degrading p85α
por: Shen, Yihui, et al.
Publicado: (2022)

Mesaconine alleviates doxorubicin-triggered cardiotoxicity and heart failure by activating PINK1-dependent cardiac mitophagy
por: Zhou, Ji-Chao, et al.
Publicado: (2023)

Bawei Chenxiang Wan Ameliorates Cardiac Hypertrophy by Activating AMPK/PPAR-α Signaling Pathway Improving Energy Metabolism
por: Zhang, Xiaoying, et al.
Publicado: (2021)

Erratum: SIRT1 activation and its effect on intercalated disc proteins as a way to reduce doxorubicin cardiotoxicity
por: Frontiers Production Office,
Publicado: (2023)

Mitochondria-dependent ferroptosis plays a pivotal role in doxorubicin cardiotoxicity
por: Tadokoro, Tomonori, et al.
Publicado: (2023)

Shenmai Injection Protects Against Doxorubicin-Induced Cardiotoxicity via Maintaining Mitochondrial Homeostasis
por: Li, Lin, et al.
Publicado: (2020)

PKC-ζ Aggravates Doxorubicin-Induced Cardiotoxicity by Inhibiting Wnt/β-Catenin Signaling
por: Cao, Yan-Jun, et al.
Publicado: (2022)

DiOHF Protects Against Doxorubicin-Induced Cardiotoxicity Through ERK1 Signaling Pathway
por: Chang, Danqi, et al.
Publicado: (2019)

Glucagon‐like peptide‐1 ameliorates cardiac lipotoxicity in diabetic cardiomyopathy via the PPARα pathway
por: Wu, Lujin, et al.
Publicado: (2018)

Resolvin D1 Attenuates Doxorubicin-Induced Cardiotoxicity by Inhibiting Inflammation, Oxidative and Endoplasmic Reticulum Stress
por: Wang, Menglong, et al.
Publicado: (2022)

Oroxylin A ameliorates AKI-to-CKD transition through maintaining PPARα-BNIP3 signaling-mediated mitochondrial homeostasis
por: Yao, Mengying, et al.
Publicado: (2022)

Glabridin Prevents Doxorubicin-Induced Cardiotoxicity Through Gut Microbiota Modulation and Colonic Macrophage Polarization in Mice
por: Huang, Keqing, et al.
Publicado: (2019)

GCN2 deficiency ameliorates doxorubicin-induced cardiotoxicity by decreasing cardiomyocyte apoptosis and myocardial oxidative stress
por: Wang, Yue, et al.
Publicado: (2018)

The Cardioprotective Mechanism of Phenylaminoethyl Selenides (PAESe) Against Doxorubicin-Induced Cardiotoxicity Involves Frataxin
por: Fu, Xiaoyu, et al.
Publicado: (2021)

Engineered biomaterial delivery strategies are used to reduce cardiotoxicity in osteosarcoma
por: Hou, Yulin, et al.
Publicado: (2023)

Tubeimoside I Ameliorates Doxorubicin-Induced Cardiotoxicity by Upregulating SIRT3
por: Zhang, Wei, et al.
Publicado: (2023)

Breviscapine remodels myocardial glucose and lipid metabolism by regulating serotonin to alleviate doxorubicin-induced cardiotoxicity
por: Li, Meng-Jiao, et al.
Publicado: (2022)

Protective effect of cafestol against doxorubicin-induced cardiotoxicity in rats by activating the Nrf2 pathway
por: Al-Kenany, Sara A., et al.
Publicado: (2023)

Piperine Alleviates Doxorubicin-Induced Cardiotoxicity via Activating PPAR-γ in Mice
por: Yan, Jie, et al.
Publicado: (2019)

Mitochondria-Targeting Small Molecules Effectively Prevent Cardiotoxicity Induced by Doxorubicin
por: Shi, Wei, et al.
Publicado: (2018)

Bailing capsule (Cordyceps sinensis) ameliorates renal triglyceride accumulation through the PPARα pathway in diabetic rats
por: Zhang, Qian, et al.
Publicado: (2022)

Bilirubin Improves Gap Junction to Alleviate Doxorubicin-Induced Cardiotoxicity by Regulating AMPK-Axl-SOCS3-Cx43 Axis
por: Zhang, Siqi, et al.
Publicado: (2022)

Evaluation of Ameliorative Effect of Quercetin and Candesartan in Doxorubicin-Induced Cardiotoxicity
por: Majhi, Sagarika, et al.
Publicado: (2022)

Cardiac SIRT1 ameliorates doxorubicin-induced cardiotoxicity by targeting sestrin 2
por: Wang(a), Jie, et al.
Publicado: (2022)

Hypoxia-ameliorated photothermal manganese dioxide nanoplatform for reversing doxorubicin resistance
por: Chen, Zhenzhen, et al.
Publicado: (2023)

Huoxue Huatan Decoction Ameliorates Myocardial Ischemia/Reperfusion Injury in Hyperlipidemic Rats via PGC-1α–PPARα and PGC-1α–NRF1–mtTFA Pathways
por: Lin, Fei, et al.
Publicado: (2020)

Neobavaisoflavone Induces Bilirubin Metabolizing Enzyme UGT1A1 via PPARα and PPARγ
por: Zhu, Ya-Di, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_82aa3bvreq49h6sqlape8h62nq