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Evolution of chest CT manifestations of COVID-19: a longitudinal study

BACKGROUND: The aim of this study was to investigate the chest CT manifestations of COVID-19 and its CT evolving process to explore its inherent outcomes. METHODS: Inpatients diagnosed with COVID-19 at the Enze Hospital from January 17, 2020 to February 15, 2020 were included. The evolving character...

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Autores principales: Kong, Min, Yang, Hai, Li, Xiaodong, Shen, Jianfei, Xu, Xinjian, Lv, Dongqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578469/
https://www.ncbi.nlm.nih.gov/pubmed/33145063
http://dx.doi.org/10.21037/jtd-20-1363
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author Kong, Min
Yang, Hai
Li, Xiaodong
Shen, Jianfei
Xu, Xinjian
Lv, Dongqing
author_facet Kong, Min
Yang, Hai
Li, Xiaodong
Shen, Jianfei
Xu, Xinjian
Lv, Dongqing
author_sort Kong, Min
collection PubMed
description BACKGROUND: The aim of this study was to investigate the chest CT manifestations of COVID-19 and its CT evolving process to explore its inherent outcomes. METHODS: Inpatients diagnosed with COVID-19 at the Enze Hospital from January 17, 2020 to February 15, 2020 were included. The evolving characteristics of CT manifestations and treatment outcomes were analyzed. RESULTS: Twenty-two patients with COVID-19 were included in the study. Clinical symptoms at the time of onset included fever (n=19) and cough (n=8). The first CT findings mainly included ground-glass opacities (GGOs) (n=18), lung consolidation (n=7), interlobular septal thickening (n=5), and fibrosis-like stripes (n=4). Dynamic CT showed GGOs, lung consolidation, and fibrosis-like stripes, all of which demonstrated a trend that initially increased in number, and then gradually decreased in number or disappeared. According to the characteristics of CT evolution. COVID-19 could be divided into early stage, progressing stage, recovery stage, and dissipation stage. The median times of the respective stages were: early stage—3 days (1–8 days) after disease onset, progressing stage—7 days (4–17 days) after onset, recovery stage—10 days (8–14 days) after onset, and dissipation stage—19.5 days (11–25 days) after onset. CONCLUSIONS: COVID-19 has an acute onset, with main imaging manifestations of different types of GGO with or without lung consolidation in the subpleural regions of the bilateral lungs. The CT manifestations of lung lesions change rapidly. The lung lesions of mild and ordinary types of COVID-19 may improve significantly or disappear in a short period after active treatment, with good prognosis. Moreover, fibrosis-like stripes may be a sign of atelectasis of sub-segment lung tissue of COVID-19 and may be a specific sign for the diagnosis of COVID-19.
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spelling pubmed-75784692020-11-02 Evolution of chest CT manifestations of COVID-19: a longitudinal study Kong, Min Yang, Hai Li, Xiaodong Shen, Jianfei Xu, Xinjian Lv, Dongqing J Thorac Dis Original Article BACKGROUND: The aim of this study was to investigate the chest CT manifestations of COVID-19 and its CT evolving process to explore its inherent outcomes. METHODS: Inpatients diagnosed with COVID-19 at the Enze Hospital from January 17, 2020 to February 15, 2020 were included. The evolving characteristics of CT manifestations and treatment outcomes were analyzed. RESULTS: Twenty-two patients with COVID-19 were included in the study. Clinical symptoms at the time of onset included fever (n=19) and cough (n=8). The first CT findings mainly included ground-glass opacities (GGOs) (n=18), lung consolidation (n=7), interlobular septal thickening (n=5), and fibrosis-like stripes (n=4). Dynamic CT showed GGOs, lung consolidation, and fibrosis-like stripes, all of which demonstrated a trend that initially increased in number, and then gradually decreased in number or disappeared. According to the characteristics of CT evolution. COVID-19 could be divided into early stage, progressing stage, recovery stage, and dissipation stage. The median times of the respective stages were: early stage—3 days (1–8 days) after disease onset, progressing stage—7 days (4–17 days) after onset, recovery stage—10 days (8–14 days) after onset, and dissipation stage—19.5 days (11–25 days) after onset. CONCLUSIONS: COVID-19 has an acute onset, with main imaging manifestations of different types of GGO with or without lung consolidation in the subpleural regions of the bilateral lungs. The CT manifestations of lung lesions change rapidly. The lung lesions of mild and ordinary types of COVID-19 may improve significantly or disappear in a short period after active treatment, with good prognosis. Moreover, fibrosis-like stripes may be a sign of atelectasis of sub-segment lung tissue of COVID-19 and may be a specific sign for the diagnosis of COVID-19. AME Publishing Company 2020-09 /pmc/articles/PMC7578469/ /pubmed/33145063 http://dx.doi.org/10.21037/jtd-20-1363 Text en 2020 Journal of Thoracic Disease. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Original Article
Kong, Min
Yang, Hai
Li, Xiaodong
Shen, Jianfei
Xu, Xinjian
Lv, Dongqing
Evolution of chest CT manifestations of COVID-19: a longitudinal study
title Evolution of chest CT manifestations of COVID-19: a longitudinal study
title_full Evolution of chest CT manifestations of COVID-19: a longitudinal study
title_fullStr Evolution of chest CT manifestations of COVID-19: a longitudinal study
title_full_unstemmed Evolution of chest CT manifestations of COVID-19: a longitudinal study
title_short Evolution of chest CT manifestations of COVID-19: a longitudinal study
title_sort evolution of chest ct manifestations of covid-19: a longitudinal study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578469/
https://www.ncbi.nlm.nih.gov/pubmed/33145063
http://dx.doi.org/10.21037/jtd-20-1363
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