Dendritic Cells and Microglia Have Non-redundant Functions in the Inflamed Brain with Protective Effects of Type 1 cDCs

Brain CD11c(+) cells share features with microglia and dendritic cells (DCs). Sterile inflammation increases brain CD11c(+) cells, but their phenotype, origin, and functions remain largely unknown. We report that, after cerebral ischemia, microglia attract DCs to the inflamed brain, and astroglia pr...

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Detalles Bibliográficos
Autores principales: Gallizioli, Mattia, Miró-Mur, Francesc, Otxoa-de-Amezaga, Amaia, Cugota, Roger, Salas-Perdomo, Angélica, Justicia, Carles, Brait, Vanessa H., Ruiz-Jaén, Francisca, Arbaizar-Rovirosa, Maria, Pedragosa, Jordi, Bonfill-Teixidor, Ester, Gelderblom, Mathias, Magnus, Tim, Cano, Eva, del Fresno, Carlos, Sancho, David, Planas, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578563/
https://www.ncbi.nlm.nih.gov/pubmed/33086061
http://dx.doi.org/10.1016/j.celrep.2020.108291

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