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Detection of genes responsible for cetuximab sensitization in colorectal cancer cells using CRISPR-Cas9

Colorectal cancer (CRC) is a common malignant tumor in digestive tract with highly invasive and metastatic capacity. Drug sensitivity remains a significant obstacle to successful chemotherapy in CRC patients. The present study aimed to explore genes related to cetuximab (CTX) sensitivity in CRC by c...

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Detalles Bibliográficos
Autores principales:	Hu, Ting-ting, Yang, Jia-wen, Yan, Ye, Chen, Ying-ying, Xue, Hai-bo, Xiang, You-qun, Ye, Le-chi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	Gene Expression & Regulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578620/ https://www.ncbi.nlm.nih.gov/pubmed/33048115 http://dx.doi.org/10.1042/BSR20201125

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