Repeated stress exposure in mid-adolescence attenuates behavioral, noradrenergic, and epigenetic effects of trauma-like stress in early adult male rats

Stress in adolescence can regulate vulnerability to traumatic stress in adulthood through region-specific epigenetic activity and catecholamine levels. We hypothesized that stress in adolescence would increase adult trauma vulnerability by impairing extinction-retention, a deficit in PTSD, by (1) al...

Descripción completa

Detalles Bibliográficos
Autores principales: Chaby, Lauren E., Sadik, Nareen, Burson, Nicole A., Lloyd, Scott, O’Donnel, Kelly, Winters, Jesse, Conti, Alana C., Liberzon, Israel, Perrine, Shane A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578655/
https://www.ncbi.nlm.nih.gov/pubmed/33087769
http://dx.doi.org/10.1038/s41598-020-74481-3

Ejemplares similares

Ejemplares similares