AXL Is a Driver of Stemness in Normal Mammary Gland and Breast Cancer

The receptor tyrosine kinase AXL is associated with epithelial plasticity in several solid tumors including breast cancer and AXL-targeting agents are currently in clinical trials. We hypothesized that AXL is a driver of stemness traits in cancer by co-option of a regulatory function normally reserv...

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Detalles Bibliográficos
Autores principales: Engelsen, Agnete S.T., Wnuk-Lipinska, Katarzyna, Bougnaud, Sebastien, Pelissier Vatter, Fanny A., Tiron, Crina, Villadsen, René, Miyano, Masaru, Lotsberg, Maria L., Madeleine, Noëlly, Panahandeh, Pouda, Dhakal, Sushil, Tan, Tuan Zea, Peters, Stacey D’mello, Grøndal, Sturla, Aziz, Sura M., Nord, Silje, Herfindal, Lars, Stampfer, Martha R., Sørlie, Therese, Brekken, Rolf A., Straume, Oddbjørn, Halberg, Nils, Gausdal, Gro, Thiery, Jean Paul, Akslen, Lars A., Petersen, Ole W., LaBarge, Mark A., Lorens, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578759/
https://www.ncbi.nlm.nih.gov/pubmed/33103086
http://dx.doi.org/10.1016/j.isci.2020.101649

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