The GEF Trio controls endothelial cell size and arterial remodeling downstream of Vegf signaling in both zebrafish and cell models

Arterial networks enlarge in response to increase in tissue metabolism to facilitate flow and nutrient delivery. Typically, the transition of a growing artery with a small diameter into a large caliber artery with a sizeable diameter occurs upon the blood flow driven change in number and shape of en...

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Detalles Bibliográficos
Autores principales: Klems, Alina, van Rijssel, Jos, Ramms, Anne S., Wild, Raphael, Hammer, Julia, Merkel, Melanie, Derenbach, Laura, Préau, Laetitia, Hinkel, Rabea, Suarez-Martinez, Irina, Schulte-Merker, Stefan, Vidal, Ramon, Sauer, Sascha, Kivelä, Riikka, Alitalo, Kari, Kupatt, Christian, van Buul, Jaap D., le Noble, Ferdinand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578835/
https://www.ncbi.nlm.nih.gov/pubmed/33087700
http://dx.doi.org/10.1038/s41467-020-19008-0

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