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Emodin inhibiting neutrophil elastase‐induced epithelial‐mesenchymal transition through Notch1 signalling in alveolar epithelial cells
The transition of alveolar type II epithelial cells into fibroblasts has been reported to cause and/or aggravate pulmonary fibrosis (PF), which is characterized by fibroblast proliferation, an enhanced production and accumulation of ECM (extracellular matrix), alveolar wall damage and functional cap...
Autores principales: | Zhou, Linshui, Gao, Rundi, Hong, Huihua, Li, Xiaojuan, Yang, Jia, Shen, Wei, Wang, Zhen, Yang, Junchao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578861/ https://www.ncbi.nlm.nih.gov/pubmed/32935466 http://dx.doi.org/10.1111/jcmm.15827 |
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