Cargando…
Phosphoinositide‐dependent Kinase‐1 (PDPK1) regulates serum/glucocorticoid‐regulated Kinase 3 (SGK3) for prostate cancer cell survival
Prostate cancer (PCa) is the most common malignancy and is the second leading cause of cancer among men globally. Using a kinome‐wide lentiviral small‐hairpin RNA (shRNA) library screen, we identified phosphoinositide‐dependent kinase‐1 (PDPK1) as a potential mediator of cell survival in PCa cells....
Autores principales: | Nalairndran, Geetha, Hassan Abdul Razack, Azad, Mai, Chun‐Wai, Fei‐Lei Chung, Felicia, Chan, Kok‐Keong, Hii, Ling‐Wei, Lim, Wei‐Meng, Chung, Ivy, Leong, Chee‐Onn |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578863/ https://www.ncbi.nlm.nih.gov/pubmed/32926495 http://dx.doi.org/10.1111/jcmm.15876 |
Ejemplares similares
-
Inhibition of Janus Kinase 1 synergizes docetaxel sensitivity in prostate cancer cells
por: Nalairndran, Geetha, et al.
Publicado: (2021) -
Mini-Review: PDPK1 (3-phosphoinositide dependent protein kinase-1), An Emerging Cancer Stem Cell Target
por: Domrachev, Bogdan, et al.
Publicado: (2021) -
Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway
por: Soo, Hsien-Chuen, et al.
Publicado: (2017) -
Identification of 11-Hydroxytephrosin and Torosaflavone A as Potential Inhibitors of 3-Phosphoinositide-Dependent Protein Kinase 1 (PDPK1): Toward Anticancer Drug Discovery
por: Atiya, Akhtar, et al.
Publicado: (2022) -
Protein Kinase Activity of Phosphoinositide 3-Kinase Regulates Cytokine-Dependent Cell Survival
por: Thomas, Daniel, et al.
Publicado: (2013)