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ATM‐Dependent Recruitment of BRD7 is required for Transcriptional Repression and DNA Repair at DNA Breaks Flanking Transcriptional Active Regions

Repair of DNA double‐strand breaks (DSBs) is essential for genome integrity, and is accompanied by transcriptional repression at the DSB regions. However, the mechanisms how DNA repair induces transcriptional inhibition remain elusive. Here, it is identified that BRD7 participates in DNA damage resp...

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Detalles Bibliográficos
Autores principales: Hu, Kaishun, Li, Yu, Wu, Wenjing, Xie, Limin, Yan, Haiyan, Cai, Yuexin, Chen, Dong, Jiang, Qiongchao, Lin, Lehang, Chen, Zhen, Liao, Jian‐You, Zhang, Yin, Koeffler, H. Phillip, Yin, Dong, Song, Erwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578904/
https://www.ncbi.nlm.nih.gov/pubmed/33101843
http://dx.doi.org/10.1002/advs.202000157

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