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An Unorthodox Mechanism Underlying Voltage Sensitivity of TRPV1 Ion Channel

While the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1) channel is a polymodal nociceptor for heat, capsaicin, and protons, the channel's responses to each of these stimuli are profoundly regulated by membrane potential, damping or even prohibiting its response at negative...

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Detalles Bibliográficos
Autores principales: Yang, Fan, Xu, Lizhen, Lee, Bo Hyun, Xiao, Xian, Yarov‐Yarovoy, Vladimir, Zheng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578911/
https://www.ncbi.nlm.nih.gov/pubmed/33101845
http://dx.doi.org/10.1002/advs.202000575