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Pomegranate Juice does not Affect the Bioavailability of Cyclosporine in Healthy Thai Volunteers

BACKGROUND: It is still controversial whether pomegranate causes drug interactions. Pomegranate juice has been shown to inhibit CYP3A in-vitro and animal studies. The co-administration of pomegranate juice with cyclosporine, a narrow therapeutic drug that is the substrate of CYP3A, might lead to dru...

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Detalles Bibliográficos
Autores principales: Anlamlert, Wirin, Sermsappasuk, Pakawadee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579232/
https://www.ncbi.nlm.nih.gov/pubmed/31924158
http://dx.doi.org/10.2174/1574884715666200110153125