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Role of endoscopic ultrasound in pediatric patients: A single tertiary center experience and review of the literature

BACKGROUND: Although endoscopic ultrasound (EUS) is now widely available and has an established role in adults, the utility of EUS and EUS-guided fine needle aspiration (EUS-FNA) in pediatrics is insufficiently described compared to adults and is supported by only a few studies. AIM: To report the e...

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Autores principales: Altonbary, Ahmed Youssef, Hakim, Hazem, Elkashef, Wagdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579528/
https://www.ncbi.nlm.nih.gov/pubmed/33133372
http://dx.doi.org/10.4253/wjge.v12.i10.355
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author Altonbary, Ahmed Youssef
Hakim, Hazem
Elkashef, Wagdi
author_facet Altonbary, Ahmed Youssef
Hakim, Hazem
Elkashef, Wagdi
author_sort Altonbary, Ahmed Youssef
collection PubMed
description BACKGROUND: Although endoscopic ultrasound (EUS) is now widely available and has an established role in adults, the utility of EUS and EUS-guided fine needle aspiration (EUS-FNA) in pediatrics is insufficiently described compared to adults and is supported by only a few studies. AIM: To report the experience of a single tertiary center in the use of EUS and EUS-FNA in a pediatric population and to further assess its safety, feasibility, and clinical impact on management. METHODS: A retrospective study of 13 children (aged 18 years or younger) identified from our medical database was conducted. A retrospective review of demographic data, procedure indications, EUS findings, and the clinical impact of EUS on the subsequent management of these patients was performed. RESULTS: During the 4-year study period, a total of 13 (1.7%) pediatric EUS examinations out of 749 EUS procedures were performed in our unit. The mean age of these 8 females and 5 males was 15.6 years (range: 6-18). Six of the 13 EUS examinations were pancreatobiliary (46.1%), followed by mediastinal 2/13 (15.4%), peri-gastric 2/13 (15.4%), abdominal lymphadenopathy 1/13 (7.7%), tracheal 1/13 (7.7%) and rectal 1/13 (7.7%). Overall, EUS-FNA was performed in 7 patients (53.8%) with a diagnostic yield of 100%. The EUS results had a significant impact on clinical care in 10/13 (77%) cases. No complications occurred in these patients during or after any of the procedures. CONCLUSION: EUS and EUS-FNA in the pediatric population are safe, feasible, and have a significant clinical impact on the subsequent management; thus avoiding invasive and unnecessary procedures.
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spelling pubmed-75795282020-10-29 Role of endoscopic ultrasound in pediatric patients: A single tertiary center experience and review of the literature Altonbary, Ahmed Youssef Hakim, Hazem Elkashef, Wagdi World J Gastrointest Endosc Retrospective Study BACKGROUND: Although endoscopic ultrasound (EUS) is now widely available and has an established role in adults, the utility of EUS and EUS-guided fine needle aspiration (EUS-FNA) in pediatrics is insufficiently described compared to adults and is supported by only a few studies. AIM: To report the experience of a single tertiary center in the use of EUS and EUS-FNA in a pediatric population and to further assess its safety, feasibility, and clinical impact on management. METHODS: A retrospective study of 13 children (aged 18 years or younger) identified from our medical database was conducted. A retrospective review of demographic data, procedure indications, EUS findings, and the clinical impact of EUS on the subsequent management of these patients was performed. RESULTS: During the 4-year study period, a total of 13 (1.7%) pediatric EUS examinations out of 749 EUS procedures were performed in our unit. The mean age of these 8 females and 5 males was 15.6 years (range: 6-18). Six of the 13 EUS examinations were pancreatobiliary (46.1%), followed by mediastinal 2/13 (15.4%), peri-gastric 2/13 (15.4%), abdominal lymphadenopathy 1/13 (7.7%), tracheal 1/13 (7.7%) and rectal 1/13 (7.7%). Overall, EUS-FNA was performed in 7 patients (53.8%) with a diagnostic yield of 100%. The EUS results had a significant impact on clinical care in 10/13 (77%) cases. No complications occurred in these patients during or after any of the procedures. CONCLUSION: EUS and EUS-FNA in the pediatric population are safe, feasible, and have a significant clinical impact on the subsequent management; thus avoiding invasive and unnecessary procedures. Baishideng Publishing Group Inc 2020-10-16 2020-10-16 /pmc/articles/PMC7579528/ /pubmed/33133372 http://dx.doi.org/10.4253/wjge.v12.i10.355 Text en ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Retrospective Study
Altonbary, Ahmed Youssef
Hakim, Hazem
Elkashef, Wagdi
Role of endoscopic ultrasound in pediatric patients: A single tertiary center experience and review of the literature
title Role of endoscopic ultrasound in pediatric patients: A single tertiary center experience and review of the literature
title_full Role of endoscopic ultrasound in pediatric patients: A single tertiary center experience and review of the literature
title_fullStr Role of endoscopic ultrasound in pediatric patients: A single tertiary center experience and review of the literature
title_full_unstemmed Role of endoscopic ultrasound in pediatric patients: A single tertiary center experience and review of the literature
title_short Role of endoscopic ultrasound in pediatric patients: A single tertiary center experience and review of the literature
title_sort role of endoscopic ultrasound in pediatric patients: a single tertiary center experience and review of the literature
topic Retrospective Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579528/
https://www.ncbi.nlm.nih.gov/pubmed/33133372
http://dx.doi.org/10.4253/wjge.v12.i10.355
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