Diaphragmatic myoclonus due to SARS-CoV-2 infection

A wide range of neurological signs and symptoms have been associated with SARS-CoV-2 infection. In the present report, we described two Italian patients diagnosed with diaphragmatic myoclonus after COVID-19. In both cases, mild lymphocytosis at cerebrospinal fluid analysis and no structural brain ch...

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Autores principales: Borroni, Barbara, Gazzina, Stefano, Dono, Fedele, Mazzoleni, Valentina, Liberini, Paolo, Carrarini, Claudia, Russo, Mirella, Pontolillo, Michela, Vecchiet, Jacopo, Onofrj, M., Bonanni, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Covid-19
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579554/
https://www.ncbi.nlm.nih.gov/pubmed/33090303
http://dx.doi.org/10.1007/s10072-020-04766-y
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author Borroni, Barbara
Gazzina, Stefano
Dono, Fedele
Mazzoleni, Valentina
Liberini, Paolo
Carrarini, Claudia
Russo, Mirella
Pontolillo, Michela
Vecchiet, Jacopo
Onofrj, M.
Bonanni, Laura
author_facet Borroni, Barbara
Gazzina, Stefano
Dono, Fedele
Mazzoleni, Valentina
Liberini, Paolo
Carrarini, Claudia
Russo, Mirella
Pontolillo, Michela
Vecchiet, Jacopo
Onofrj, M.
Bonanni, Laura
author_sort Borroni, Barbara
collection PubMed
description A wide range of neurological signs and symptoms have been associated with SARS-CoV-2 infection. In the present report, we described two Italian patients diagnosed with diaphragmatic myoclonus after COVID-19. In both cases, mild lymphocytosis at cerebrospinal fluid analysis and no structural brain changes were reported. The pathophysiological origin of the myoclonus in the two cases was different. In case 1, electroencephalogram did not reveal any cortical correlates and brain imaging of the spine was unremarkable, while in case 2, cortical origin of myoclonus was demonstrated. With the present two cases, we confirm and extend the neurological manifestations of SARS-CoV-2 infection. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10072-020-04766-y) contains supplementary material, which is available to authorized users.
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spelling pubmed-75795542020-10-22 Diaphragmatic myoclonus due to SARS-CoV-2 infection Borroni, Barbara Gazzina, Stefano Dono, Fedele Mazzoleni, Valentina Liberini, Paolo Carrarini, Claudia Russo, Mirella Pontolillo, Michela Vecchiet, Jacopo Onofrj, M. Bonanni, Laura Neurol Sci Covid-19 A wide range of neurological signs and symptoms have been associated with SARS-CoV-2 infection. In the present report, we described two Italian patients diagnosed with diaphragmatic myoclonus after COVID-19. In both cases, mild lymphocytosis at cerebrospinal fluid analysis and no structural brain changes were reported. The pathophysiological origin of the myoclonus in the two cases was different. In case 1, electroencephalogram did not reveal any cortical correlates and brain imaging of the spine was unremarkable, while in case 2, cortical origin of myoclonus was demonstrated. With the present two cases, we confirm and extend the neurological manifestations of SARS-CoV-2 infection. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10072-020-04766-y) contains supplementary material, which is available to authorized users. Springer International Publishing 2020-10-22 2020 /pmc/articles/PMC7579554/ /pubmed/33090303 http://dx.doi.org/10.1007/s10072-020-04766-y Text en © Fondazione Società Italiana di Neurologia 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Covid-19
Borroni, Barbara
Gazzina, Stefano
Dono, Fedele
Mazzoleni, Valentina
Liberini, Paolo
Carrarini, Claudia
Russo, Mirella
Pontolillo, Michela
Vecchiet, Jacopo
Onofrj, M.
Bonanni, Laura
Diaphragmatic myoclonus due to SARS-CoV-2 infection
title Diaphragmatic myoclonus due to SARS-CoV-2 infection
title_full Diaphragmatic myoclonus due to SARS-CoV-2 infection
title_fullStr Diaphragmatic myoclonus due to SARS-CoV-2 infection
title_full_unstemmed Diaphragmatic myoclonus due to SARS-CoV-2 infection
title_short Diaphragmatic myoclonus due to SARS-CoV-2 infection
title_sort diaphragmatic myoclonus due to sars-cov-2 infection
topic Covid-19
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579554/
https://www.ncbi.nlm.nih.gov/pubmed/33090303
http://dx.doi.org/10.1007/s10072-020-04766-y
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