Cargando…
A novel voltage-clamp/dye uptake assay reveals saturable transport of molecules through CALHM1 and connexin channels
Large-pore channels permeable to small molecules such as ATP, in addition to atomic ions, are emerging as important regulators in health and disease. Nonetheless, their mechanisms of molecular permeation and selectivity remain mostly unexplored. Combining fluorescence microscopy and electrophysiolog...
Autores principales: | Gaete, Pablo S., Lillo, Mauricio A., López, William, Liu, Yu, Jiang, Wenjuan, Luo, Yun, Harris, Andrew L., Contreras, Jorge E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579738/ https://www.ncbi.nlm.nih.gov/pubmed/33074302 http://dx.doi.org/10.1085/jgp.202012607 |
Ejemplares similares
-
Glutathione release through connexin hemichannels: Implications for chemical modification of pores permeable to large molecules
por: Tong, Xuhui, et al.
Publicado: (2015) -
Confocal imaging of transmembrane voltage by SEER of di-8-ANEPPS
por: Manno, Carlo, et al.
Publicado: (2013) -
Inferring subunit stoichiometry from single molecule
photobleaching
por: Hines, Keegan E.
Publicado: (2013) -
A method for imaging single molecules at the plasma membrane of live cells within tissue slices
por: Mashanov, Gregory I., et al.
Publicado: (2020) -
A high-throughput fluorescence lifetime-based assay to detect binding of myosin-binding protein C to F-actin
por: Bunch, Thomas A., et al.
Publicado: (2021)