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A novel voltage-clamp/dye uptake assay reveals saturable transport of molecules through CALHM1 and connexin channels

Large-pore channels permeable to small molecules such as ATP, in addition to atomic ions, are emerging as important regulators in health and disease. Nonetheless, their mechanisms of molecular permeation and selectivity remain mostly unexplored. Combining fluorescence microscopy and electrophysiolog...

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Detalles Bibliográficos
Autores principales:	Gaete, Pablo S., Lillo, Mauricio A., López, William, Liu, Yu, Jiang, Wenjuan, Luo, Yun, Harris, Andrew L., Contreras, Jorge E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2020
Materias:	Methods and Approaches
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579738/ https://www.ncbi.nlm.nih.gov/pubmed/33074302 http://dx.doi.org/10.1085/jgp.202012607

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