Cargando…

Genomic amplification of chromosome 20q13.33 is the early biomarker for the development of sporadic colorectal carcinoma

BACKGROUND: Colorectal carcinoma (CRC) is the third most common cancer in the world and also the third leading cause of cancer-related mortality in Taiwan. CRC tumorigenesis is a multistep process, starting from mutations causing loss of function of tumor suppressor genes, canonically demonstrated i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bui, Vo-Minh-Hoang, Mettling, Clément, Jou, Jonathan, Sun, H. Sunny
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579792/ https://www.ncbi.nlm.nih.gov/pubmed/33087131 http://dx.doi.org/10.1186/s12920-020-00776-z

Ejemplares similares

Duplications at 19q13.33 in patients with neurodevelopmental disorders
por: Pérez-Palma, Eduardo, et al.
Publicado: (2018)

Somatic Mutational Landscape in Mexican Patients: CDH1 Mutations and chr20q13.33 Amplifications Are Associated with Diffuse-Type Gastric Adenocarcinoma
por: Cerrato-Izaguirre, Dennis, et al.
Publicado: (2022)

19q13.33→qter trisomy in a girl with intellectual impairment and seizures
por: Carvalheira, Gianna, et al.
Publicado: (2014)

A Genotype-First Approach for the Molecular and Clinical Characterization of Uncommon De Novo Microdeletion of 20q13.33
por: Traylor, Ryan N., et al.
Publicado: (2010)

Fine mapping the KLK3 locus on chromosome 19q13.33 associated with prostate cancer susceptibility and PSA levels
por: Parikh, Hemang, et al.
Publicado: (2011)

hHSS1: a novel secreted factor and suppressor of glioma growth located at chromosome 19q13.33
por: Junes-Gill, Katiana S., et al.
Publicado: (2010)

A comprehensive resequence analysis of the KLK15–KLK3–KLK2 locus on chromosome 19q13.33
por: Parikh, Hemang, et al.
Publicado: (2009)

A functional variant on 20q13.33 related to glioma risk alters enhancer activity and modulates expression of multiple genes
por: Ali, Mourad Wagdy, et al.
Publicado: (2020)

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33
por: Houlston, Richard S, et al.
Publicado: (2010)

POGLUT1, the putative effector gene driven by rs2293370 in primary biliary cholangitis susceptibility locus chromosome 3q13.33
por: Hitomi, Yuki, et al.
Publicado: (2019)

Placental methylome reveals a 22q13.33 brain regulatory gene locus associated with autism
por: Zhu, Yihui, et al.
Publicado: (2022)

Compound phenotype in a girl with r(22), concomitant microdeletion 22q13.32-q13.33 and mosaic monosomy 22
por: Kashevarova, Anna A., et al.
Publicado: (2018)

De Novo Deletion of Chromosome 20q13.33 in a Patient with Tracheo-esophageal Fistula, Cardiac Defects and Genitourinary Anomalies Implicates GTPBP5 as a Candidate Gene
por: Solomon, Benjamin D, et al.
Publicado: (2011)

Expanding the Clinical Phenotype of 19q Interstitial Deletions: A New Case with 19q13.32-q13.33 Deletion and Short Review of the Literature
por: Shelby, Elena-Silvia, et al.
Publicado: (2022)

The 12p13.33/RAD52 Locus and Genetic Susceptibility to Squamous Cell Cancers of Upper Aerodigestive Tract
por: Delahaye-Sourdeix, Manon, et al.
Publicado: (2015)

Loss of heterozygosity in sporadic breast tumours at the BRCA2 locus on chromosome 13q12-q13.
por: Cleton-Jansen, A. M., et al.
Publicado: (1995)

Genetic polymorphisms at 19q13.33 are associated with [−2]proPSA (p2PSA) levels and provide additional predictive value to prostate health index for prostate cancer
por: Huang, Da, et al.
Publicado: (2021)

Allelic loss at chromosome 13q12-q13 is associated with poor prognosis in familial and sporadic breast cancer.
por: van den Berg, J., et al.
Publicado: (1996)

A boy with conduct disorder (CD), attention deficit hyperactivity disorder (ADHD), borderline intellectual disability, and 47,XXY syndrome in combination with a 7q11.23 duplication, 11p15.5 deletion, and 20q13.33 deletion
por: Kolaitis, Gerasimos, et al.
Publicado: (2016)

Chromosomal amplifications, 3q gain and deletions of 2q33-q37 are the frequent genetic changes in cervical carcinoma
por: Rao, Pulivarthi H, et al.
Publicado: (2004)

Temporal Chondroblastoma with a Novel Chromosomal Translocation (2;5) (q33;q13)
por: Carlson, Andrew P., et al.
Publicado: (2011)

Cell Models for Chromosome 20q11.21 Amplification and Drug Sensitivities in Colorectal Cancer
por: Voutsadakis, Ioannis A.
Publicado: (2021)

Chromosome 20q Amplification Regulates in Vitro Response to Kinesin-5 Inhibitor
por: Jackson, Aimee L., et al.
Publicado: (2008)

Ser1333 phosphorylation indicates ROCKI activation
por: Chuang, Hsiang-Hao, et al.
Publicado: (2013)

Variable Phenotypes of Epilepsy, Intellectual Disability, and Schizophrenia Caused by 12p13.33–p13.32 Terminal Microdeletion in a Korean Family: A Case Report and Literature Review
por: Han, Ji Yoon, et al.
Publicado: (2021)

A Histone Map of Human Chromosome 20q13.12
por: Akan, Pelin, et al.
Publicado: (2009)

Endothelial protein C receptor is overexpressed in colorectal cancer as a result of amplification and hypomethylation of chromosome 20q
por: Lal, Neeraj, et al.
Publicado: (2017)

Amplification of the 20q Chromosomal Arm Occurs Early in Tumorigenic Transformation and May Initiate Cancer
por: Tabach, Yuval, et al.
Publicado: (2011)

Frequency, prognostic impact, and subtype association of 8p12, 8q24, 11q13, 12p13, 17q12, and 20q13 amplifications in breast cancers
por: Letessier, Anne, et al.
Publicado: (2006)

11q13.3q13.4 deletion plus 9q21.13q21.33 duplication in an affected girl arising from a familial four‐way balanced chromosomal translocation
por: Zhang, Qinxin, et al.
Publicado: (2023)

Multigene Panel Germline Testing of 1333 Czech Patients with Ovarian Cancer
por: Lhotova, Klara, et al.
Publicado: (2020)

1333. Prognostic Factors Associated with Complications of Acute Hematogenous Osteomyelitis in Children
por: Clemente, Adriana Sarmiento, et al.
Publicado: (2022)

DNA amplifications at 20q13 and MDM2 define distinct subsets of evolved breast and ovarian tumours.
por: Courjal, F., et al.
Publicado: (1996)

Frequent Loss of Heterozygosity at the MCC Locus on Chromosome 5q21‐22 in Sporadic Colorectal Carcinomas
por: Miki, Yoshio, et al.
Publicado: (1991)

Recurrent Sporadic Bilateral Retinoblastoma in a Child with 13q Deletion Syndrome
por: Qadar, Laila Tul, et al.
Publicado: (2020)

Chromosome 11q13 amplification correlates with poor response and prognosis to PD-1 blockade in unresectable hepatocellular carcinoma
por: Yan, Kai, et al.
Publicado: (2023)

A Copy Number Variant on Chromosome 20q13.3 Implicated in Thinness and Severe Obesity
por: Hasstedt, Sandra J., et al.
Publicado: (2015)

Mutation of Serine 1333 in the ATR HEAT Repeats Creates a Hyperactive Kinase
por: Luzwick, Jessica W., et al.
Publicado: (2014)

Gain of Chromosome 20q Is an Indicator of Poor Prognosis in Colorectal Cancer
por: Postma, C., et al.
Publicado: (2007)

A high resolution physical and RH map of pig chromosome 6q1.2 and comparative analysis with human chromosome 19q13.1
por: Martins-Wess, Flávia, et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_v4hjb1rfjkfhpivb0q4jplli4e