Cargando…
Understanding and responding to COVID-19 in Wales: protocol for a privacy-protecting data platform for enhanced epidemiology and evaluation of interventions
INTRODUCTION: The emergence of the novel respiratory SARS-CoV-2 and subsequent COVID-19 pandemic have required rapid assimilation of population-level data to understand and control the spread of infection in the general and vulnerable populations. Rapid analyses are needed to inform policy developme...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580065/ https://www.ncbi.nlm.nih.gov/pubmed/33087383 http://dx.doi.org/10.1136/bmjopen-2020-043010 |
_version_ | 1783598718605328384 |
---|---|
author | Lyons, Jane Akbari, Ashley Torabi, Fatemeh Davies, Gareth I North, Laura Griffiths, Rowena Bailey, Rowena Hollinghurst, Joseph Fry, Richard Turner, Samantha L Thompson, Daniel Rafferty, James Mizen, Amy Orton, Chris Thompson, Simon Au-Yeung, Lee Cross, Lynsey Gravenor, Mike B Brophy, Sinead Lucini, Biagio John, Ann Szakmany, Tamas Davies, Jan Davies, Chris Thomas, Daniel Rh Williams, Christopher Emmerson, Chris Cottrell, Simon Connor, Thomas R Taylor, Chris Pugh, Richard J Diggle, Peter John, Gareth Scourfield, Simon Hunt, Joe Cunningham, Anne M Helliwell, Kathryn Lyons, Ronan |
author_facet | Lyons, Jane Akbari, Ashley Torabi, Fatemeh Davies, Gareth I North, Laura Griffiths, Rowena Bailey, Rowena Hollinghurst, Joseph Fry, Richard Turner, Samantha L Thompson, Daniel Rafferty, James Mizen, Amy Orton, Chris Thompson, Simon Au-Yeung, Lee Cross, Lynsey Gravenor, Mike B Brophy, Sinead Lucini, Biagio John, Ann Szakmany, Tamas Davies, Jan Davies, Chris Thomas, Daniel Rh Williams, Christopher Emmerson, Chris Cottrell, Simon Connor, Thomas R Taylor, Chris Pugh, Richard J Diggle, Peter John, Gareth Scourfield, Simon Hunt, Joe Cunningham, Anne M Helliwell, Kathryn Lyons, Ronan |
author_sort | Lyons, Jane |
collection | PubMed |
description | INTRODUCTION: The emergence of the novel respiratory SARS-CoV-2 and subsequent COVID-19 pandemic have required rapid assimilation of population-level data to understand and control the spread of infection in the general and vulnerable populations. Rapid analyses are needed to inform policy development and target interventions to at-risk groups to prevent serious health outcomes. We aim to provide an accessible research platform to determine demographic, socioeconomic and clinical risk factors for infection, morbidity and mortality of COVID-19, to measure the impact of COVID-19 on healthcare utilisation and long-term health, and to enable the evaluation of natural experiments of policy interventions. METHODS AND ANALYSIS: Two privacy-protecting population-level cohorts have been created and derived from multisourced demographic and healthcare data. The C20 cohort consists of 3.2 million people in Wales on the 1 January 2020 with follow-up until 31 May 2020. The complete cohort dataset will be updated monthly with some individual datasets available daily. The C16 cohort consists of 3 million people in Wales on the 1 January 2016 with follow-up to 31 December 2019. C16 is designed as a counterfactual cohort to provide contextual comparative population data on disease, health service utilisation and mortality. Study outcomes will: (a) characterise the epidemiology of COVID-19, (b) assess socioeconomic and demographic influences on infection and outcomes, (c) measure the impact of COVID-19 on short -term and longer-term population outcomes and (d) undertake studies on the transmission and spatial spread of infection. ETHICS AND DISSEMINATION: The Secure Anonymised Information Linkage-independent Information Governance Review Panel has approved this study. The study findings will be presented to policy groups, public meetings, national and international conferences, and published in peer-reviewed journals. |
format | Online Article Text |
id | pubmed-7580065 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-75800652020-10-27 Understanding and responding to COVID-19 in Wales: protocol for a privacy-protecting data platform for enhanced epidemiology and evaluation of interventions Lyons, Jane Akbari, Ashley Torabi, Fatemeh Davies, Gareth I North, Laura Griffiths, Rowena Bailey, Rowena Hollinghurst, Joseph Fry, Richard Turner, Samantha L Thompson, Daniel Rafferty, James Mizen, Amy Orton, Chris Thompson, Simon Au-Yeung, Lee Cross, Lynsey Gravenor, Mike B Brophy, Sinead Lucini, Biagio John, Ann Szakmany, Tamas Davies, Jan Davies, Chris Thomas, Daniel Rh Williams, Christopher Emmerson, Chris Cottrell, Simon Connor, Thomas R Taylor, Chris Pugh, Richard J Diggle, Peter John, Gareth Scourfield, Simon Hunt, Joe Cunningham, Anne M Helliwell, Kathryn Lyons, Ronan BMJ Open Public Health INTRODUCTION: The emergence of the novel respiratory SARS-CoV-2 and subsequent COVID-19 pandemic have required rapid assimilation of population-level data to understand and control the spread of infection in the general and vulnerable populations. Rapid analyses are needed to inform policy development and target interventions to at-risk groups to prevent serious health outcomes. We aim to provide an accessible research platform to determine demographic, socioeconomic and clinical risk factors for infection, morbidity and mortality of COVID-19, to measure the impact of COVID-19 on healthcare utilisation and long-term health, and to enable the evaluation of natural experiments of policy interventions. METHODS AND ANALYSIS: Two privacy-protecting population-level cohorts have been created and derived from multisourced demographic and healthcare data. The C20 cohort consists of 3.2 million people in Wales on the 1 January 2020 with follow-up until 31 May 2020. The complete cohort dataset will be updated monthly with some individual datasets available daily. The C16 cohort consists of 3 million people in Wales on the 1 January 2016 with follow-up to 31 December 2019. C16 is designed as a counterfactual cohort to provide contextual comparative population data on disease, health service utilisation and mortality. Study outcomes will: (a) characterise the epidemiology of COVID-19, (b) assess socioeconomic and demographic influences on infection and outcomes, (c) measure the impact of COVID-19 on short -term and longer-term population outcomes and (d) undertake studies on the transmission and spatial spread of infection. ETHICS AND DISSEMINATION: The Secure Anonymised Information Linkage-independent Information Governance Review Panel has approved this study. The study findings will be presented to policy groups, public meetings, national and international conferences, and published in peer-reviewed journals. BMJ Publishing Group 2020-10-21 /pmc/articles/PMC7580065/ /pubmed/33087383 http://dx.doi.org/10.1136/bmjopen-2020-043010 Text en © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/ https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Public Health Lyons, Jane Akbari, Ashley Torabi, Fatemeh Davies, Gareth I North, Laura Griffiths, Rowena Bailey, Rowena Hollinghurst, Joseph Fry, Richard Turner, Samantha L Thompson, Daniel Rafferty, James Mizen, Amy Orton, Chris Thompson, Simon Au-Yeung, Lee Cross, Lynsey Gravenor, Mike B Brophy, Sinead Lucini, Biagio John, Ann Szakmany, Tamas Davies, Jan Davies, Chris Thomas, Daniel Rh Williams, Christopher Emmerson, Chris Cottrell, Simon Connor, Thomas R Taylor, Chris Pugh, Richard J Diggle, Peter John, Gareth Scourfield, Simon Hunt, Joe Cunningham, Anne M Helliwell, Kathryn Lyons, Ronan Understanding and responding to COVID-19 in Wales: protocol for a privacy-protecting data platform for enhanced epidemiology and evaluation of interventions |
title | Understanding and responding to COVID-19 in Wales: protocol for a privacy-protecting data platform for enhanced epidemiology and evaluation of interventions |
title_full | Understanding and responding to COVID-19 in Wales: protocol for a privacy-protecting data platform for enhanced epidemiology and evaluation of interventions |
title_fullStr | Understanding and responding to COVID-19 in Wales: protocol for a privacy-protecting data platform for enhanced epidemiology and evaluation of interventions |
title_full_unstemmed | Understanding and responding to COVID-19 in Wales: protocol for a privacy-protecting data platform for enhanced epidemiology and evaluation of interventions |
title_short | Understanding and responding to COVID-19 in Wales: protocol for a privacy-protecting data platform for enhanced epidemiology and evaluation of interventions |
title_sort | understanding and responding to covid-19 in wales: protocol for a privacy-protecting data platform for enhanced epidemiology and evaluation of interventions |
topic | Public Health |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580065/ https://www.ncbi.nlm.nih.gov/pubmed/33087383 http://dx.doi.org/10.1136/bmjopen-2020-043010 |
work_keys_str_mv | AT lyonsjane understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT akbariashley understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT torabifatemeh understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT daviesgarethi understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT northlaura understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT griffithsrowena understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT baileyrowena understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT hollinghurstjoseph understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT fryrichard understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT turnersamanthal understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT thompsondaniel understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT raffertyjames understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT mizenamy understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT ortonchris understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT thompsonsimon understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT auyeunglee understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT crosslynsey understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT gravenormikeb understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT brophysinead understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT lucinibiagio understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT johnann understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT szakmanytamas understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT daviesjan understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT davieschris understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT thomasdanielrh understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT williamschristopher understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT emmersonchris understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT cottrellsimon understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT connorthomasr understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT taylorchris understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT pughrichardj understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT digglepeter understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT johngareth understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT scourfieldsimon understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT huntjoe understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT cunninghamannem understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT helliwellkathryn understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions AT lyonsronan understandingandrespondingtocovid19inwalesprotocolforaprivacyprotectingdataplatformforenhancedepidemiologyandevaluationofinterventions |